| |
Ventilation only
|
S-ALI control
|
ECMO control
|
S-ALI + ECMO
|
|---|
|
B
|
24 h
|
B
|
24 h
|
B
|
24 h
|
B
|
24 h
|
|---|
|
Full blood examination
|
|
WCC, ×109/L
|
9.8 (3.1)
|
10.2 (2.2)
|
7.8 (2.1)
|
21.8 (8.3)a
|
7.0 (2.2)
|
7.9 (1.7)a
|
6.6 (1.2)
|
9.1 (3.8)a
|
|
RCC, ×1012/L
|
8.7 (0.68)
|
6.2 (0.6)
|
8.5 (0.78)
|
8.9 (1.36)a
|
8.0 (1.2)
|
4.8 (0.54)a
|
8.3 (0.87)
|
7.3 (1.2)
|
|
Hb, g/L
|
97.8 (9.1)
|
70.3 (6.1)
|
96.1 (9.4)
|
99.1 (12)a
|
89.3 (12)
|
54.3 (5.4)a
|
93.4 (11)
|
83.5 (12)
|
|
Hct
|
0.28 (0.02)
|
0.20 (0.02)
|
0.28 (0.03)
|
0.29 (0.04)a
|
0.26 (0.04)
|
0.16 (0.01)a
|
0.28 (0.03)
|
0.24 (0.04)
|
|
PLT, ×109/L
|
341 (173)
|
190 (110)
|
355 (186)
|
203 (111)
|
471 (95)
|
260 (80)
|
364 (140)
|
199 (60)
|
|
Routine coagulation tests
|
|
PT, seconds
|
14.5 (1)
|
17.3 (1)
|
15.9 (1.1)
|
34.4 (5.4)a
|
12.9 (0.6)
|
17.4 (2.1)
|
14.3 (0.9)
|
35 (6.7)a
|
|
aPTT, seconds
|
33 (6)
|
139 (76)
|
31 (6)
|
165 (42)
|
26 (4.6)
|
122 (64)
|
30 (6)
|
158 (57)
|
|
Fibrinogen, g/L
|
2.5 (0.54)
|
3.5 (0.13)
|
2.1 (0.62)
|
2.5 (0.34)a
|
2.9 (0.47)
|
2.6 (0.16)a
|
3.0 (0.97)
|
1.5 (0.5)a
|
|
d-dimer, ng/ml
|
215 (85)
|
198 (70)
|
146 (44)
|
139 (82)
|
435 (192)
|
343 (217)
|
406 (213)
|
213 (136)
|
|
TCT, seconds
|
13 (0)
|
21 (7)
|
13 (0)
|
81 (84)
|
12 (1)
|
156 (81)
|
13 (1)
|
44 (69)
|
|
Specialised coagulation tests
|
|
FVIII, %
|
1531 (413)
|
1390 (414)
|
1347 (417)
|
1544 (238)
|
891(235)
|
408 (51)a
|
904 (166)
|
531 (242)a
|
|
FXII, %
|
103 (17.7)
|
75 (10)
|
96 (30.9)
|
29 (11.5)a
|
151 (37.7)
|
67 (12.4)
|
107 (20.2)
|
16 (6.7)a
|
|
Protein C, %
|
21.5 (2.5)
|
21.5 (1.3)
|
21 (7.4)
|
12.1 (3.2)
|
55 (13.4)
|
50 (11.2)
|
46 (11.4)
|
14 (4.5)a
|
|
vWAg, %
|
136 (22.3)
|
130 (25.8)
|
96 (31.9)
|
140 (18.2)
|
94 (47.6)
|
88 (10.9)a
|
129 (30)
|
96 (25.3)a
|
|
AT, %
|
85.8 (7.3)
|
58.3 (6.6)
|
84.1 (3.9)
|
27.1 (3.2)a
|
93.7 (8.8)
|
62.7 (6)
|
92.3 (1.9)
|
22 (4.3)a
|
-
Abbreviations: aPTT Activated partial thromboplastin time, AT Anti-thrombin, B baseline, ECMO Extracorporeal membrane oxygenation, FVIII Factor VIII, FXII Factor XII, Hb Haemoglobin, Hct Haematocrit, PLT Platelets, PT Prothrombin time, RCC Red cell count, S-ALI Smoke-induced acute lung injury, TCT Thrombin clotting time, vWAg von Willebrand factor antigen, WCC White cell count
- Data are presented as mean (±SD)
-
a
P < 0.05 over time vs ventilation only
