Monocyte programmed death ligand-1 expression is an early marker for predicting infectious complications in acute pancreatitis

Table 4 Univariate and multivariate logistic regression analysis for infectious complications

Elements	Univariate analysis			Multivariate analysis
Elements	OR	95% CI	p Value	OR	95% CI	p Value
Age	1.038	1.001–1.077	0.041	1.025	0.969–1.084	0.386
APACHE II score	1.249	1.097–1.422	0.001	1.305	1.079–1.578	0.006
Lymphocyte count on day 1 × 10⁹/L	0.821	0.691–0.975	0.025	0.956	0.697–0.761	0.691
Percentage of HLA-DR expression on CD14⁺ monocytes on day 1	0.959	0.923–0.996	0.031	0.923	0.869–0.981	0.01
Percentage of PD-1 expression on CD4⁺ lymphocytes on day 1	1.070	1.006–1.137	0.031	1.046	0.956–1.143	0.327
Percentage of PD-L1 expression on CD14⁺ monocytes on day 1	1.075	1.016–1.138	0.013	1.098	1.005–1.200	0.036

Abbreviations: APACHE Acute Physiology and Chronic Health Evaluation, HLA-DR Human leukocyte antigen-DR, PD-1 Programmed cell death receptor 1, PD-L1 Programmed cell death receptor ligand 1

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