| Hospital survivors (n = 12) | Hospital nonsurvivors (n = 34) | p value |
---|---|---|---|
Age (years) | 47.6 ± 14.8 | 58.8 ± 14.3 | 0.029 |
Gender (M/F) | 11/1 | 25/9 | 0.252 |
SOFA score | 8.3 ± 2.5 | 14.0 ± 3.6 | <0.001 |
MELD score | 20.9 ± 10.7 | 33.0 ± 9.9 | 0.001 |
Child–Pugh score | 10 (7.3–11.8) | 12 (11–13.3) | 0.005 |
ACTH (pg/ml) | 8.7 (7.5–25.5) | 20.7 (13.1–35.1) | 0.084 |
Baseline cortisol (nmol/L) | 484 (381–796) | 821 (508–1312) | 0.026 |
Peak cortisol (nmol/L) | 955 (633–1258) | 993 (807–1549) | 0.354 |
Cortisol increment (nmol/L) | 359 (257–428) | 200 (110–252) | 0.011 |
Baseline DHEAS (nmol/L) | 1099 (787–2627) | 622 (403–1006) | 0.002 |
Peak DHEAS (nmol/L) | 1286 (1118–2874) | 699 (429–1115) | <0.001 |
DHEAS increment (nmol/L) | 236 (179–391) | 41 (10–96) | <0.001 |
Baseline DHEAS/cortisol ratio | 2.86 ± 1.40 | 0.92 ± 0.73 | 0.001 |
IL-6 (pg/ml) | 110 (54–233) | 571 (247.25–924) | 0.004 |
TNF-α (pg/ml) | 10 (5.5–25) | 45.5 (31.25–78.25) | 0.001 |