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Fig. 2 | Critical Care

Fig. 2

From: The common promoter polymorphism rs11666254 downregulates FPR2/ALX expression and increases risk of sepsis in patients with severe trauma

Fig. 2

rs11666254 polymorphism and lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α production. The whole-blood samples collected from 98 trauma patients were treated as shown. TNF-α production was determined using a sandwich enzyme-linked immunosorbent assay. One-way analysis of variance was used to assess statistical significance. P = 0.001 for dominant association, GG vs GA + AA, P = 0.003 for recessive association. P = 0.029 for GG vs GA; P = 0.006 for GG vs AA; P = 0.187 for GA vs AA. There was no significant difference between genotypes before LPS stimulation

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