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Fig. 3 | Critical Care

Fig. 3

From: Evaluation of early antimicrobial therapy adaptation guided by the BetaLACTA® test: a case-control study

Fig. 3

Empirical antimicrobial therapy adaptations in the conventional and BetaLACTA® test (BLT)-guided groups. In the conventional adaptation group, only one early de-escalation occurred once the results of the culture of the microbiological sample were available. The other 32 modifications occurred after the results of the antibiotic susceptibility tests, in particular 14 escalations for which patients received an inappropriate beta-lactam antibiotic. Conversely, in the BLT-guided adaptation group, 9 early escalations and 17 early de-escalations occurred once the results of the culture of the microbiological samples were available, among which no false positives and one false negative occurred. Amox. amoxicillin, Clav. clavulanate, Pip. piperacillin, Taz. Tazobactam, ESBL Extended-spectrum beta-lactamases, 3rd GC and 4th GC, 3rd and 4th generation cephalosporins

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