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Fig. 3 | Critical Care

Fig. 3

From: Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids

Fig. 3

Leukocyte rolling flux (top) (a) and leukocyte adhesion (bottom) (b) in post-capillary venules from sham-procedure rats (4 rats, 12 vessels) and from rats subjected to shock/resuscitation with normal saline (NS) (5 rats, 17 vessels), lactated Ringer’s solution (LR) (5 rats, 22 vessels), 5% albumin (4 rats, 12 vessels) and fresh frozen plasma (FFP) (4 rats, 18 vessels). Significant increase in leukocyte rolling (a) and leukocyte adhesion (b) after resuscitation with NS compared to sham, LR, albumin and FFP (p < 0.05). Leukocytes, stationary for a period of time >30 s were considered firmly adhered to the endothelium surface. The graph shows the number of adherent leukocytes per 100-μm venule length. Box plots display median, interquartile range, minimum and maximum. Dots on the box plots represent outliers. aSignificantly different from the sham group. bSignificantly different from the 5% albumin group. cSignificantly different from the FFP group. dSignificantly different from the LR group

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