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Fig. 1 | Critical Care

Fig. 1

From: Transcriptome modulation by hydrocortisone in severe burn shock: ancillary analysis of a prospective randomized trial

Fig. 1

Modulation of gene expression after burn shock. a Heatmap representation of expression in genes modulated by burn injury over time. Gene expression (rows) is color-coded from blue to orange. Individual values were averaged according to sample time (columns), and the associated number of samples is presented above each column. Although this analysis was performed only in patients on placebo, we included the representation of the identified gene modulation in hydrocortisone-treated patients alongside. Five (1 to 5) clusters were identified by unsupervised analysis, according to a similar longitudinal profile of expression, and are illustrated as boxplots (b-f). Hydrocortisone-treated patients are in purple and placebo-treated patients are in green. S1 to S4 sample times day 0, day 1, day 5 and day 7, respectively, HV healthy volunteers

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