From: Severe varicella-zoster virus pneumonia: a multicenter cohort study
Variables | |
---|---|
Pulmonary symptoms (n = 102) | |
Temperature, °C | 39.2 (38.7–39.9) |
Dyspnea | 96 (94%) |
Cough | 45 (44%) |
Hemoptysis | 9 (9%) |
Chest pain | 10 (10%) |
Acute respiratory failure at ICU admission | 69 (68%) |
Chest X-ray at ICU admission (n = 97, 95%) | |
Normal | 1 (1%) |
Unilateral alveolar opacities | 7 (8%) |
Bilateral alveolar opacities | 23 (24%) |
Unilateral interstitial pattern | 1 (1%) |
Bilateral interstitial pattern | 68 (75%) |
Lung CT scan (n = 31, 30%) | |
Normal | 0 (0%) |
Ground glass opacities | 11 (39%) |
Nodules | 14 (50%) |
Consolidations | 14 (50%) |
Interlobular septal thickening | 2 (8%) |
Pleural effusion | 8 (29%) |
Fiberoptic bronchoscopy (n = 35, 35%)a | |
Inflammatory mucosa | 6 (43%) |
Vesicular lesions on bronchial mucosa | 6 (43%) |
Normal | 2 (14%) |
Bronchoalveolar lavage (n = 29, 28%) | |
Diffuse intra-alveolar hemorrhageb | 5 (29%) |
Cell count/μL (n = 11, 38%) | 300,000 (215,000–675,000) |
Macrophages, % of total cells | 50 (22–65) |
Lymphocytes, % of total cells | 7.5 (5–20) |
Neutrophils, % of total cells | 31 (5–63) |
Eosinophils, % of total cells | 0 (0–2) |
Siderophages, % of total cells | 0 (0–5) |
Virus identified by PCR in the BAL (24 samples) | 23 (96%) |