Protein S100 as outcome predictor after out-of-hospital cardiac arrest and targeted temperature management at 33 °C and 36 °C

Table 3 Multivariable analysis with multiple imputation: clinical variables and S100

			95% CI
S100 + clinical	Effect	Odds ratio	Lower	Upper	p Value
Intercept	−3.670		0.01	0.11	<0.001
S100 at 24 h	1.828	6.221	0.77	50.55	0.09
S100 at 48 h	0.873	2.395	0.13	45.81	0.56
S100 at 72 h	1.594	4.926	0.21	117.39	0.32
Target temperature	0.085	1.089	0.75	1.59	0.66
Age	0.062	1.064	1.05	1.08	<0.001
Time CA to ROSC	0.022	1.022	1.01	1.03	<0.001
Lactate level on admission	−0.001	0.999	0.95	1.05	0.98
Sex	−0.271	0.762	0.47	1.24	0.27
Bystander CPR performed	−0.527	0.590	0.39	0.90	0.02
VT/VF versus PEA/asystole	−1.431	0.239	0.13	0.43	<0.001
ROSC after bystander defibrillation	−1.560	0.210	0.05	0.88	0.03
Shock on admission	0.160	1.173	0.62	2.21	0.98

Abbreviations: CA Cardiac arrest, CPR Cardiopulmonary resuscitation, PEA Pulseless electrical activity, ROSC Return of spontaneous circulation, VF Ventricular fibrillation, VT Ventricular tachycardia

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