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Table 3 Multivariable analysis with multiple imputation: clinical variables and S100

From: Protein S100 as outcome predictor after out-of-hospital cardiac arrest and targeted temperature management at 33 °C and 36 °C

    95% CI  
S100 + clinical Effect Odds ratio Lower Upper p Value
Intercept −3.670   0.01 0.11 <0.001
S100 at 24 h 1.828 6.221 0.77 50.55 0.09
S100 at 48 h 0.873 2.395 0.13 45.81 0.56
S100 at 72 h 1.594 4.926 0.21 117.39 0.32
Target temperature 0.085 1.089 0.75 1.59 0.66
Age 0.062 1.064 1.05 1.08 <0.001
Time CA to ROSC 0.022 1.022 1.01 1.03 <0.001
Lactate level on admission −0.001 0.999 0.95 1.05 0.98
Sex −0.271 0.762 0.47 1.24 0.27
Bystander CPR performed −0.527 0.590 0.39 0.90 0.02
VT/VF versus PEA/asystole −1.431 0.239 0.13 0.43 <0.001
ROSC after bystander defibrillation −1.560 0.210 0.05 0.88 0.03
Shock on admission 0.160 1.173 0.62 2.21 0.98
  1. Abbreviations: CA Cardiac arrest, CPR Cardiopulmonary resuscitation, PEA Pulseless electrical activity, ROSC Return of spontaneous circulation, VF Ventricular fibrillation, VT Ventricular tachycardia