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Table 4 SI level (L/mU/minute) median [IQR] comparison between survivors and non-survivors using 6-h blocks

From: Untangling glycaemia and mortality in critical care

Hours Cohort 1: (n = 145 patients)
Survivors (SI S ) L/mU/minute × 10−4 Non-survivors (SI NS ) L/mU/minute × 10−4 Median SI S − SI NS [95% CI] L/mU/minute × 10−4
Day 1
 0–5 1.39 [0.50, 2.54] 1.64 [0.63, 2.63] −0.25 [−0.60, 0.06] ×
 6–11 1.94 [1.11, 3.35] 2.58 [1.42, 3.97] −0.63 [−1.04, −0.11] a,b ×
 12–17 2.54 [1.42, 4.48] 3.39 [1.63, 4.79] −0.79 [−1.46, 0.22] ×
 18–23 2.76 [1.57, 5.09] 3.22 [1.93, 5.16] −0.42 [−0.93, 0.14] ×
Day 2
 24–29 2.96 [1.65, 4.98] 3.30 [1.81, 4.85] −0.30 [−0.73, 0.13] ×
 30–35 3.08 [1.83, 5.73] 4.34 [2.35, 7.21] −1.23 [−2.16, −0.20] a ×
 36–41 3.13 [1.81, 5.44] 3.42 [2.23, 5.36] −0.29 [−1.01, 0.43] ×
 42–47 3.22 [1.81, 5.47] 4.43 [2.48, 6.24] −0.25 [−0.94, 0.16] ×
Day 3
 48–53 3.28 [1.95, 5.36] 4.83 [3.13, 8.63] −1.57 [−2.36, −0.97] a,b ×
 54–59 3.55 [2.03, 5.50] 4.65 [2.53, 7.27] −1.12 [−2.04, −0.40] a ×
 60–65 3.39 [2.18, 5.18] 4.19 [2.71, 6.83] −0.81 [−1.59, −0.01] a ×
 66–71 3.40 [2.43, 5.07] 3.86 [2.43, 8.30] −0.47 [−1.43, 0.16] ×
Hours Cohort 2: (n = 80 patients)
Survivors (SI S ) L/mU/minute × 10−4 Non − Survivors (SI NS ) L/mU/minute × 10−4 Median SI S − SI NS [95% CI] L/mU/minute × 10−4
Day 1
 0–5 1.39 [0.43, 2.45] 1.38 [0.30, 2.54] −0.00 [−0.52, 0.57] ×
 6–11 1.90 [0.92, 3.66] 2.22 [1.15, 3.62] −0.33 [−1.00, 0.02] ×
 12–17 2.36 [1.37, 4.48] 2.46 [1.46, 4.50] −0.12 [−1.19, 0.61] ×
 18–23 2.63 [1.53, 4.47] 2.94 [1.87, 4.50] −0.30 [−0.81, 0.14] ×
Day 2
 24–29 2.95 [1.53, 4.52] 3.19 [1.65, 4.82] −0.26 [−0.75, 0.22] ×
 30–35 3.04 [1.88, 5.07] 3.56 [2.24, 6.85] −0.55 [−1.95, 0.12] ×
 36–41 3.06 [1.79, 4.94] 3.15 [2.14, 5.04] −0.10 [−0.79, 0.51] ×
 42–47 3.21 [1.80, 5.23] 3.41 [2.93, 5.27] −0.24 [−0.86, 0.22] ×
Day 3
 48–53 3.31 [1.98, 5.30] 4.59 [3.03, 8.20] −1.26 [−1.84, −0.41] a,b ×
 54–59 3.59 [2.09, 5.50] 4.37 [2.43, 7.36] −0.87 [−1.81, −0.09] a ×
 60–65 3.45 [2.18, 5.24] 3.94 [2.62, 6.53] −0.48 [−1.37, 0.25] ×
 66–71 3.41 [2.43, 5.21] 3.68 [2.42, 7.56] −0.30 [−1.20, 0.24] ×
  1. Non-equivalence is indicated by ×, Equivalence is indicated by
  2. aHours where the medians are statistically different (95% CI on difference in medians does not cross zero)
  3. bDifferences remaining significant after Bonferroni correction (99.6% CI on difference in medians does not cross zero)
  4. Bootstrapped confidence interval (CI) in bold is statistically significant to p<0.05