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Table 2 Characteristics of the study cohort stratified by NRBCs (n = 2569)

From: Nucleated red blood cells, critical illness survivors and postdischarge outcomes: a cohort study

 

0/μl

1-100/μl

101-200/μl

>200/μl

P value (chi-square test)

N

1867

487

101

114

 

Male gender

1025 (55)

248 (51)

60 (59)

57 (50)

0.22

Nonwhite race

380 (20)

109 (22)

20 (20)

27 (24)

0.66

Age (years)

60.1 ± 18.5

62.7 ± 16.4

63.2 ± 15.4

61.4 ± 17.4

0.014*

Surgical patient type

785 (42)

253 (52)

55 (54)

54 (47)

<0.001

Deyo–Charlson Index

    

<0.001

 0

444 (24)

63 (13)

9 (9)

17 (15)

 

 1–2

473 (25)

111 (23)

21 (21)

23 (20)

 

 3–6

394 (21)

113 (23)

30 (30)

29 (25)

 

 ≥7

556 (30)

200 (41)

41 (41)

45 (40)

 

Sepsis

118 (6)

77 (16)

22 (22)

24 (21)

<0.001

Pneumonia

293 (16)

125 (26)

31 (31)

38 (33)

<0.001

Noncardiac acute respiratory failure

98 (5)

45 (9)

13 (13)

13 (11)

<0.001

Acute organ failure

    

<0.001

 0

721 (39)

94 (19)

10 (10)

18 (16)

 

 1

663 (36)

169 (35)

37 (37)

26 (23)

 

 2

337 (18)

118 (24)

25 (25)

28 (25)

 

 ≥3

146 (8)

106 (22)

29 (29)

42 (37)

 

Leukemia or myelodysplastic syndrome

131 (7)

55 (11)

19 (19)

24 (21)

<0.001

Hematocrit

35.5 ± 6.6

31.2 ± 6.6

29.2 ± 7.4

28.8 ± 7.0

<0.001

Red cell distribution width

13.9 (13.1–15.1)

15.3 (14.2–17.1)

16.3 (15.1–18.0)

17.1 (15.5–19.3)

 

Chronic kidney disease

510 (27)

197 (40)

39 (39)

54 (47)

<0.001

Transfusions

0 (0–0)

0 (0–1)

1 (0–3)

0 (0–2)

<0.001†

Acute Organ Failure score

9.5 ± 4.4

10.9 ± 4.9

11.9 ± 5.1

12.0 ± 5.9

<0.001*

NRBCs

0 (0–0)

40 (20–60)

140 (120–170)

375 (270–690)

<0.001†

Postdischarge mortality rate (%)

     

 30-day

58 (3.1)

34 (7.0)

12 (11.9)

17 (14.9)

<0.001

 90-day

111 (6.0)

57 (11.7)

16 (15.8)

25 (21.9)

<0.001

  1. Data presented as n (%), mean ± SD, or median (interquartile range)
  2. *P value determined by ANOVA
  3. † P value determined by Kruskal–Wallis test
  4. NRBC nucleated red blood cell