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Table 1 Characteristics of patients in the study

From: The negative effect of initial high-dose methylprednisolone and tapering regimen for acute respiratory distress syndrome: a retrospective propensity matched cohort study

Variables High-dose group Low-dose group P value
(n = 21) (n = 165)
Age, years 70 (64–80) 77 (69–83) 0.135
Sex, male, n (%) 11 (47.8) 105 (63.6) 0.316
Cause of ARDS pulmonary, n (%) 15 (65.2) 101 (61.2) 0.363
Cause of ARDS infection, n (%) 16 (69.6) 111 (67.3) 0.408
PaO2/FIO2 ratio 107.0 (60.1–140.4) 106.8 (77.2–153.6) 0.179
white blood cells (/mm3) 12500 (8250–15200) 9700 (5300–15150) 0.538
CRP (mg/dL) 8.90 (5.33–21.02) 16.1. (9.59–25.00) 0.031
LDH (IU/L) 478.0 (326.5–699.5) 324.0 (250.0–435.0) 0.011
Platelets (×104/mm3) 17.0 (9.6–29.0) 18.4 (11.6–25.1) 0.664
Albumin (g/dL) 2.8 (2.6–3.2) 2.9 (2.4–3.2) 0.634
PEEP (cmH2O) 8.0 (7.0–10.0) 8.0 (8.0–12.0) 0.022
PIP (cmH2O)a 18.0 (10.0–25.0) 22.0 (18.0–25.0) 0.109
Tidal volume (mL)b 450.0 (357.5–468.8) 420.0 (350.0–490.0) 0.520
ARDS severity mild/moderate/severe 0/11/10 15/78/72 0.354
HRCT score 257.0 (209.1–290.8) 209.9 (183.4–283.0) 0.214
APACHE II score 19.0 (16.0–25.5) 22.0 (18.0–25.0) 0.240
SOFA score 6.0 (5.5–9.5) 7.0 (5.0–10.0) 0.494
McCabe classification category 1/2/3 19/1/1 145/10/10 0.942
  1. Data are presented as median (IQR), unless otherwise stated. ARDS acute respiratory distress syndrome, PaO 2 arterial oxygen tension, FiO 2 fraction of inspired oxygen, CRP C-reactive protein, LDH lactate dehydrogenase, ALB serum albumin, PEEP positive end-expiratory pressure, PIP peak inspiratory pressure, CT computed tomography, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sequential Organ Failure Assessment, HRCT high-resolution computed tomography
  2. aHigh-dose group (n = 18), low-dose group (n = 122)
  3. bHigh-dose group (n = 14), low-dose group (n = 119)