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Table 2 Respiratory parameters varying pressure support and NAVA assist levels

From: Effects of neurally adjusted ventilatory assist on air distribution and dead space in patients with acute exacerbation of chronic obstructive pulmonary disease

Ventilator mode 50% 100% 150%
PSV NAVA PSV NAVA PSV NAVA
Assist pressure (cmH2O) 6.73 ± 0.70 6.88 ± 1.08 8.20 ± 0.73b 7.68 ± 1.39 9.74 ± 1.23c 7.94 ± 1.25
Ppeak (cmH2O) 11.35 ± 0.91 12.88 ± 3.30 16.01 ± 0.84 16.52 ± 4.82 20.77 ± 0.94 18.81 ± 4.29
EAdi (μV) 14.69 ± 8.72 11.67 ± 8.64 11.48 ± 7.75 11.43 ± 8.13 14.33 ± 6.87c 11.86 ± 6.34
Respiratory rate (/min) 22.58 ± 5.28 22.34 ± 4.58 21.00 ± 7.71 23.06 ± 5.40 18.10 ± 6.67 19.59 ± 5.52
MVe (L/min) 7.66 ± 2.58 7.39 ± 2.20 8.58 ± 4.22 8.41 ± 3.32 8.84 ± 3.48c 7.65 ± 3.00
Inspiratory time (s) 0.93 ± 0.21 1.02 ± 0.14 1.10 ± 0.45 1.01 ± 0.21 1.22 ± 0.55 1.05 ± 0.18
Vt (L) 0.35 ± 0.09 0.34 ± 0.10 0.42 ± 0.14 0.38 ± 0.14 0.53 ± 0.21c 0.40 ± 0.11
Trigger delay (s) 0.17 ± 0.08a 0.05 ± 0.02 0.25 ± 0.23b 0.06 ± 0.06 0.34 ± 0.18c 0.06 ± 0.05
Cycle delay (s) 0.11 ± 0.10a 0.02 ± 0.01 0.32 ± 0.49b 0.06 ± 0.11 0.48 ± 0.72c 0.05 ± 0.07
Work of breathing (μV∙s) 7.31 ± 5.76 6.20 ± 5.96 6.10 ± 5.83 5.11 ± 2.31 7.33 ± 4.13 6.26 ± 3.91
Work of trigger (μV∙s) 1.20 ± 0.68a 0.89 ± 0.36 1.52 ± 1.25b 1.11 ± 0.59 2.17 ± 1.08c 1.20 ± 0.92
(ROI1 + 2) × Vt (L/min) 0.20 ± 0.16a 0.17 ± 0.13 0.26 ± 0.15 0.20 ± 0.14 0.26 ± 013c 0.21 ± 0.14
(ROI3 + 4) × Vt (L/min) 0.21 ± 0.12 0.19 ± 0.09 0.20 ± 0.12 0.20 ± 0.11 0.24 ± 0.12 0.22 ± 0.10
  1. EAdi electrical activity of the diaphragm, MVe minute ventilatory volume, NAVA neutrally-adjusted ventilator assist, Ppeak peak pressure, PSV pressure support ventilation, ROI regions of interest, Vt tidal volume
  2. aSignificant different versus NAVA 50%
  3. bSignificant different versus NAVA 100%
  4. cSignificant different versus NAVA 150%