Table 1 Characteristics of patients at risk for developing acute respiratory distress syndrome
From: Circulating microparticle levels are reduced in patients with ARDS
Variable | Subjects who do not develop ARDS (n = 190) | Subjects who develop ARDS (n = 90) | p Value |
|---|---|---|---|
Age, years | 54 (40–66) | 54 (44–64) | 0.769 |
Male sex | 64% | 60% | 0.598 |
ARDS risk factor (n) | |||
 Sepsis | 44 | 18 |  |
 Pneumonia | 14 | 14 | |
 Severe trauma | 81 | 37 | |
 Multiple transfusions | 12 | 3 | |
 Aspiration | 6 | 12 | |
Mechanically ventilated | 66% | 83% | 0.003 |
PaO2/FiO2 ratio | 222 (129–309) | 141 (95–214) | <0.001 |
SpO2/FiO2 ratio | 223 (147–256) | 154 (93–235) | <0.001 |
APACHE II score | 25 (20–31) | 27 (23–33) | 0.017 |
MPs at ICU day 2, μM | 5.0 (2.1–12.1) | 2.9 (1.7–7.5) | 0.011 |
MPs at ICU day 4, μM | 4.5 (2.1–9.2) | 4.2 (2.1–7.2) | 0.430 |
Clot time at ICU day 2 (sec) | 212 (185–250) | 218 (194–255) | 0.227 |
Clot time at ICU day 4 (sec) | 228 (192–254) | 252 (221–299) | 0.014 |
Ventilator-free days | 24 (15–27) | 19 (7–23) | <0.001 |
Hospital mortality | 16% | 23% | 0.138 |