From: Cost analysis of the very elderly admitted to intensive care units
Variable | Coefficient (95% CI) | P value | Coefficient (95% CI) | P value |
---|---|---|---|---|
Hospital cohort (n = 1671) | Survivors to discharge (n = 1,086) | Decedents in hospital (n = 585) | ||
Age (older) | −0.139 (−0.021, −0.007) | 0.039 | −0.029 (−0.051, −0.007) | 0.008 |
Sex (female) | −0.092 (−0.207, 0.022) | 0.113 | −0.034 (−0.289, 0.221) | 0.796 |
Admission APACHE II score (greater) | 0.031 (0.023, 0.039) | 0.000 | 0.001 (−0.012, 0.014) | 0.926 |
Baseline SOFA score (greater) | −0.005 (−0.028, 0.018) | 0.661 | −0.084 (−0.114, −0.053) | 0.000 |
Charlson comorbidity index (greater) | −0.035 (−0.069, −0.000) | 0.048 | 0.024 (−0.019, 0.067) | 0.281 |
Admission type | ||||
Surgical elective vs. medical | −0.133 (−0.287, 0.021) | 0.091 | 0.193 (−0.191, 0.577) | 0.324 |
Surgical emergency vs. medical | 0.076 (−0.065, 0.218) | 0.290 | 0.091 (−0.169, 0.351) | 0.494 |
Primary ICU diagnosis | ||||
Respiratory vs. cardiovascular | 0.461 (0.294, 0.627) | 0.000 | 0.690 (0.270, 1.111) | 0.001 |
Gastrointestinal vs. cardiovascular | 0.150 (0.004, 0.295) | 0.043 | 0.277 (−0.088, 0.642) | 0.137 |
Sepsis vs. cardiovascular | 0.177 (−0.029, 0.382) | 0.092 | 0.538 (0.238, 0.839) | 0.000 |
Other vs. cardiovascular | 0.174 (0.020, 0.328) | 0.027 | −0.210 (−0.463, 0.042) | 0.103 |
Longitudinal cohort (n = 610) | Survivors to discharge (n = 452) | Decedents in hospital (n = 158) | ||
Frailty index >4/7 | −0.001 (−0.071, 0.069) | 0.977 | 0.044 (−0.044, 0.132) | 0.325 |
Residence in a nursing home | −0.321 (−0.633, −0.010) | 0.043 | 0.046 (−0.485, 0.577) | 0.864 |
Family preference for life-sustaining treatment | ||||
Comfort care vs. life support | −0.253 (−0.433, −0.073) | 0.006 | −0.402 (−0.650, −0.155) | 0.001 |
Unsure/unclear/missing vs. life support | −0.429 (−0.635, −0.223) | 0.000 | −0.393 (−0.814, 0.028) | 0.067 |
Presence of advance directive | 0.122 (−0.050, 0.294) | 0.165 | 0.214 (−0.010, 0.438) | 0.061 |