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Table 1 Clinical characteristics of the patients

From: Pre-admission functional status impacts the performance of the APACHE IV model of mortality prediction in critically ill patients

 

FS1

FS2

FS3

FS1 vs FS2

FS1 vs FS3

Number

7714

1728

196

  

Domicile

 Home

7644

932

87

  

 Assisted living

31

116

9

 

 Rehabilitation/SNF

38

688

100

 

Age

64 (49–77)

80 (70–86)

75 (56–86)

<0.0001

<0.0001

Charlson

1 (0–2)

2 (1–4)

2 (1–3)

<0.0001

<0.0001

Diagnostic category (%)

 Medical

56.2

78.4

89.8

<0.0001

<0.0001

 Surgical

31.2

16.0

9.2

<0.0001

<0.0001

 Trauma

12.6

5.6

1.0

<0.0001

<0.0001

Diabetes mellitus (%)

19.7

29.3

22.2

<0.0001

0.4371

APACHE II comorbidities (%)

 Pulmonary

5.4

17.1

31.6

<0.0001

<0.0001

 Cardiac

7.1

22.2

13.3

<0.0001

0.0015

 End-stage renal disease

2.6

8.7

2.0

<0.0001

0.7681

 Portal hypertension

2.3

2.0

1.5

0.6973

0.6180

 Metastatic cancer

6.5

9.3

3.6

0.0051

0.1369

APACHE II score

12 (8–18)

20 (15–26)

22 (18–28)

<0.0001

<0.0001

APACHE IV score

44 (31–63)

69 (54–90)

75 (56–94)

<0.0001

<0.0001

APIV PM (%)

14.8 (22.2)

32.0 (27.4)

32.8 (24.7)

<0.0001

<0.0001

Ventilation (%)

30.5

43.8

59.2

<0.0001

<0.0001

ICU LOS

1.4 (0.8–2.8)

1.9 (1.0–4.4)

2.5 (1.2–6.6)

<0.0001

<0.0001

Mortality (%)

9.9

29.7

29.6

<0.0001

<0.0001

OE MR

0.67

0.93

0.90

<0.0001

<0.0001

  1. FS functional status, FS1 independent in performing activities of daily living (ADL), FS2 partly dependent in performing ADL, FS3 fully dependent in performing ADL, SNF skilled nursing facility, APIV PM Acute Physiology and Chronic Health Evaluation IV (APACHE IV) predicted mortality, LOS length of stay, OE MR observed-expected mortality ratio (using hospital discharge status and APIV PM)