Table 4 Most significant metabolites/ features changed between two cohorts for diagnosis and prognosis studies
From: Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia
| Â | Diagnosis of H1N1 pneumonia from positive bacterial culture pneumonia | Diagnosis of H1N1 pneumonia from ventilated ICU controls | Prognosis of mortality of H1N1 pneumonia (non-survivors vs. survivors) | |||
|---|---|---|---|---|---|---|
Decreased in H1N1 | Increased in H1N1 | Decreased in H1N1 | Increased in H1N1 | Decreased in H1N1 nonsurvivors | Increased in H1N1 nonsurvivors | |
NMR | Citrate Fumarate 3-Methyl,2-Isovalerate Alanine Tyrosine Methionine Histidine 4-Hydroxybutyrate | Acetoacetate Beta-alanine Formate Dimethylamine Carnitine Glycine | Isopropanol Citrate Taurine Glycine 2-Oxoglutarate Glutamine Alanine Serine | Dimethylamine Beta-alanine Aspartate Phenylalanine Formate 3-Hydroxyisovalerate Fumarate O-Phosphocholine Adipate Choline 2-Hydroxyisovalerate Proline Ornithine | 2-Oxoglutarate Dimethylamine Isopropanol Carnitine 2-Hydroxisovalerate Lactate Phenylalanine Acetate Tyrosine | 2-Aminobutyrate Acetoacetate 2-Hydroxybutyrate Arginine 3-Hydroxybutyrate |
GC-MSa | Uric acid Tyrosine Citric acid Asparagine Myoinositol Lysine Arabinonic acid Threonine Aspartic acid Threonic acid | Gulonic acid Pentadecane 2-amino Butanoic acid Alkane Quinic acid Benzoic acid | Galactose Lactic acid Glucose Pyroglutamic acid Galactopyranoside Glyceric acid Fructose Beta alanine Glycerol Glycine 3-hydroxyl Butanoic acid Phenylalanine | Heptadecanoic acid Phosphoric acid Hexadecanoic acid Octadecenoic acid Octadecane Quinic acid | Threonic acid Dodecane Decanoic acid 2-Amino, Butanoic acid Valine Glycerol | Methionine Pentadecane 4, Amino, Benzoic acid Hydroxylamine |