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Table 1 Baseline characteristics and clinical outcomes of included patients

From: Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit

Variable All patients (n = 152) Emergency department (n = 102) Hospital wards (n = 50) p value
Age 64 (51–75) 64 (48–76) 64 (53–71) 0.73
Female 69 (45) 51 (50) 18 (36) 0.12
Race
 White 98 (64) 64 (63) 34 (68) 0.59
 Black 17 (11) 12 (12) 5 (10) 1.00
 Hispanic 23 (15) 18 (18) 5 (10) 0.24
 Other 14 (9) 8 (8) 6 (12) 0.56
Medical history
 Heart disease 40 (26) 31 (30) 9 (18) 0.11
 Diabetes mellitus 26 (17) 19 (19) 7 (14) 0.64
 COPD 10 (7) 9 (9) 1 (2) 0.17
 CKD 29 (19) 19 (19) 10 (20) 0.83
 Malignancy, any 69 (45) 36 (35) 33 (66) 0.0005
 Malignancy, hematologic 43 (28) 18 (18) 25 (50) <0.0001
 Immunosuppression 66 (43) 36 (35) 30 (60) 0.005
Pneumonia 62 (41) 40 (39) 22 (44) 0.60
Acute kidney injurya 86 (57) 61 (60) 25 (50) 0.29
APACHE II score 25 (18–31) 25 (17–30) 26 (20–33) 0.08
Positive cultures 102 (67) 64 (63) 38 (76) 0.14
Confirmed bacteremia 38 (25) 26 (25) 12 (24) 1.00
Adjudicated infectionb 133 (88) 89 (87) 44 (88) 1.00
Vasopressors in patients with adjudicated infection 68 (45) 45 (44) 23 (46) 0.86
ARDSc 16 (11) 9 (9) 7 (14) 0.4
In-hospital mortality 29 (19) 12 (12) 17 (34) 0.002
ICU-free daysd 22 (14–25) 23 (19–25) 20 (0–24) 0.03
Ventilator-free dayse 28 (20–28) 28 (23–28) 23 (18–28) 0.002
Any organ dysfunction-free daysf 4 (0–11) 9 (0–11) 0 (0–5) 0.001
Renal dysfunction-free daysf 13 (7–14) 14 (9–14) 12 (2–14) 0.15
  1. Data are presented as median (interquartile range) or number (%) and compared with the Mann Whitney U test or the Fisher’s exact test, respectively
  2. Abbreviations: COPD chronic obstructive pulmonary disease, CKD chronic kidney disease, APACHE II Acute Physiology and Chronic Health Evaluation II, ARDS acute respiratory distress syndrome, ICU intensive care unit
  3. aDefined as an increase in serum creatinine of 0.3 mg/dL or >50% from baseline
  4. bOn the basis of clinical context, microbiological findings, and radiological studies
  5. cDefined according to the Berlin definition
  6. dFrom ICU admission to day 28
  7. eFrom initiation of invasive mechanical ventilation to day 28
  8. fFrom ICU admission to day 14