Table 1 Baseline characteristics and clinical outcomes of included patients
Variable | All patients (n = 152) | Emergency department (n = 102) | Hospital wards (n = 50) | p value |
|---|---|---|---|---|
Age | 64 (51–75) | 64 (48–76) | 64 (53–71) | 0.73 |
Female | 69 (45) | 51 (50) | 18 (36) | 0.12 |
Race | ||||
White | 98 (64) | 64 (63) | 34 (68) | 0.59 |
Black | 17 (11) | 12 (12) | 5 (10) | 1.00 |
Hispanic | 23 (15) | 18 (18) | 5 (10) | 0.24 |
Other | 14 (9) | 8 (8) | 6 (12) | 0.56 |
Medical history | ||||
Heart disease | 40 (26) | 31 (30) | 9 (18) | 0.11 |
Diabetes mellitus | 26 (17) | 19 (19) | 7 (14) | 0.64 |
COPD | 10 (7) | 9 (9) | 1 (2) | 0.17 |
CKD | 29 (19) | 19 (19) | 10 (20) | 0.83 |
Malignancy, any | 69 (45) | 36 (35) | 33 (66) | 0.0005 |
Malignancy, hematologic | 43 (28) | 18 (18) | 25 (50) | <0.0001 |
Immunosuppression | 66 (43) | 36 (35) | 30 (60) | 0.005 |
Pneumonia | 62 (41) | 40 (39) | 22 (44) | 0.60 |
Acute kidney injurya | 86 (57) | 61 (60) | 25 (50) | 0.29 |
APACHE II score | 25 (18–31) | 25 (17–30) | 26 (20–33) | 0.08 |
Positive cultures | 102 (67) | 64 (63) | 38 (76) | 0.14 |
Confirmed bacteremia | 38 (25) | 26 (25) | 12 (24) | 1.00 |
Adjudicated infectionb | 133 (88) | 89 (87) | 44 (88) | 1.00 |
Vasopressors in patients with adjudicated infection | 68 (45) | 45 (44) | 23 (46) | 0.86 |
ARDSc | 16 (11) | 9 (9) | 7 (14) | 0.4 |
In-hospital mortality | 29 (19) | 12 (12) | 17 (34) | 0.002 |
ICU-free daysd | 22 (14–25) | 23 (19–25) | 20 (0–24) | 0.03 |
Ventilator-free dayse | 28 (20–28) | 28 (23–28) | 23 (18–28) | 0.002 |
Any organ dysfunction-free daysf | 4 (0–11) | 9 (0–11) | 0 (0–5) | 0.001 |
Renal dysfunction-free daysf | 13 (7–14) | 14 (9–14) | 12 (2–14) | 0.15 |