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Table 3 Association of admission glucocorticoid levels with short-term adverse outcome in community-acquired pneumonia

From: Time-dependent association of glucocorticoids with adverse outcome in community-acquired pneumonia: a 6-year prospective cohort study

Entire cohort (N = 285) Adverse outcome at 30 days (death and/or ICU admission)
  OR (95% CI) p Value
Cortisol
 Logistic regression analyses
  Univariate model 4.16 (95% CI 1.22–14.12) 0.022
  Multivariate modela 3.85 (95% CI 1.10–13.49) 0.035
11-Deoxycortisol
 Logistic regression analyses   
  Univariate model 1.33 (95% CI 0.84–2.11) 0.216
  Multivariate modela 1.30 (95% CI 0.80–2.14) 0.293
Cortisone
 Logistic regression analyses
  Univariate model 1.89 (95% CI 0.59–1.03) 0.280
  Multivariate modela 3.25 (95% CI 0.84–12.68) 0.089
Corticosterone
 Logistic regression analyses
  Univariate model 1.41 (95% CI 0.81–2.47) 0.225
  Multivariate modela 1.44 (95% CI 0.79–2.62) 0.234
  1. ICU, Intensive care unit
  2. Data for univariate and multivariate logistic regression models are presented as OR (95% CI), p value; p < 0.05 is considered statistically significant. Bold values indicate statistical significance. All hormone levels were log-transformed, and thus the OR corresponds to a tenfold increase in levels
  3. aMultivariate model is adjusted for age, sex, and comorbidities (coronary artery disease, cerebrovascular disease, chronic kidney disease, neoplastic disease)