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Table 1 Comparison of predictive value of variables used to determine fluid responsiveness in mechanically ventilated patients in three systematic reviews

From: Use of ‘tidal volume challenge’ to improve the reliability of pulse pressure variation

Systematic review/metaanalysis Publication year Types of studies Patient type Variable AUC (95% confidence interval)
Marik et al. [7] 2009 29 studies
685 patients
variable tidal volume
ICU and OR patients PPV 0.94 (0.93–0.95)
SPV 0.86 (0.82–0.90)
SVV 0.84 (0.78–0.88)
LVEDA 0.64 (0.53–0.74)
GEDV 0.56 (0.37–0.67)
CVP 0.55 (0.48–0.62)
Hong et al. [9] 2014 19 studies
850 patients
variable tidal volume
Only ICU patients PPV 0.88 (0.84–0.92)
SVV 0.84 (0.79–0.89)
Yang and Du [10] 2014 22 studies
807 patients
tidal volume > 8 ml/kg
Only ICU patients PPV 0.94 (0.91–0.95)
  1. AUC area under the curve, ICU intensive care unit, OR operating room, PPV pulse pressure variation, SPV systolic pressure variation, SVV stroke volume variation, LVEDA left ventricular end‐diastolic area, GEDV global end‐diastolic volume, CVP central venous pressure