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Table 1 Demographic and clinical characteristics of the 95 patients enrolled in the study

From: Decreased cytokine production by mononuclear cells after severe gram-negative infections: early clinical signs and association with final outcome

Characteristics Data
Males/females, n (%) 52 (54.7%)/43 (45.3%)
Age, years, mean ± SD 68.8 ± 17.0
APACHE II score, mean ± SD 13.83 ± 7.86
PaO2/FiO2, mmHg, mean ± SD 307.6 ± 129.4
White blood cells, count/mm3, mean ± SD 14,735.0 ± 7717.0
C-reactive protein, mg/L mean ± SD 137.2 ± 97.3
Type of infection
 Acute pyelonephritis, n (%) 45 (47.4%)
 Acute intra-abdominal infection, n (%) 31 (32.6%)
 Primary gram-negative bacteraemia, n (%) 19 (20.0%)
Failing organs on enrolment, n (%) 25 (26.3%)
Acute respiratory distress syndrome, n (%) 16 (16.8%)
Acute coagulopathy 13 (13.7%)
Acute kidney injury 12 (12.6%)
Cardiovascular failure 12 (12.6%)
Isolated pathogens in blood and/or urine, n (%)
Escherichia coli 25 (26.3%)
Klebsiella pneumoniae 8 (8.4%)
Proteus mirabilis 5 (5.3%)
Pseudomonas aeruginosa 3 (3.2%)
Acinetobacter baumannii 3 (3.2%)
 Other gram-negative bacteria 8 (8.4%)
Co-existing disorders, n (%)
 Type 2 diabetes mellitus 29 (30.5%)
 Solid tumour malignancy 22 (23.2%)
 Chronic renal disease 17 (17.9%)
 Chronic obstructive pulmonary disease 15 (15.8%)
 Chronic heart failure 9 (9.5%)
Predisposing factors, n (%)
 Cerebral stroke 14 (14.7%)
 Nephrolithiasis 11 (11.6%)
 Gallstones 12 (12.6%)
 Multiple injuries 3 (3.2%)
  1. APACHE Acute Physiology and Chronic Health Evaluation, PaO 2 /FiO 2 Ratio of partial pressure arterial oxygen and fraction of inspired oxygen