Table 1 Demographic and clinical characteristics of the 95 patients enrolled in the study
Characteristics | Data |
|---|---|
Males/females, n (%) | 52 (54.7%)/43 (45.3%) |
Age, years, mean ± SD | 68.8 ± 17.0 |
APACHE II score, mean ± SD | 13.83 ± 7.86 |
PaO2/FiO2, mmHg, mean ± SD | 307.6 ± 129.4 |
White blood cells, count/mm3, mean ± SD | 14,735.0 ± 7717.0 |
C-reactive protein, mg/L mean ± SD | 137.2 ± 97.3 |
Type of infection | |
Acute pyelonephritis, n (%) | 45 (47.4%) |
Acute intra-abdominal infection, n (%) | 31 (32.6%) |
Primary gram-negative bacteraemia, n (%) | 19 (20.0%) |
Failing organs on enrolment, n (%) | 25 (26.3%) |
Acute respiratory distress syndrome, n (%) | 16 (16.8%) |
Acute coagulopathy | 13 (13.7%) |
Acute kidney injury | 12 (12.6%) |
Cardiovascular failure | 12 (12.6%) |
Isolated pathogens in blood and/or urine, n (%) | |
Escherichia coli | 25 (26.3%) |
Klebsiella pneumoniae | 8 (8.4%) |
Proteus mirabilis | 5 (5.3%) |
Pseudomonas aeruginosa | 3 (3.2%) |
Acinetobacter baumannii | 3 (3.2%) |
Other gram-negative bacteria | 8 (8.4%) |
Co-existing disorders, n (%) | |
Type 2 diabetes mellitus | 29 (30.5%) |
Solid tumour malignancy | 22 (23.2%) |
Chronic renal disease | 17 (17.9%) |
Chronic obstructive pulmonary disease | 15 (15.8%) |
Chronic heart failure | 9 (9.5%) |
Predisposing factors, n (%) | |
Cerebral stroke | 14 (14.7%) |
Nephrolithiasis | 11 (11.6%) |
Gallstones | 12 (12.6%) |
Multiple injuries | 3 (3.2%) |