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Table 1 Baseline characteristics of the study cohort

From: Catecholamines as outcome markers in isolated traumatic brain injury: the COMA-TBI study

Characteristic

All patients

Outcome at 6 months

p value

Favorable (GOSE 5–8)

Unfavorable (GOSE 1–4)

Demographics

 Frequency

174

65 (37.4)

109 (62.6)

--

 Age (years)

47.5 ± 21.2

37.5 ± 16.5

53.7 ± 21.4

<0.001

 Male

130 (74.7)

53 (40.8)

77 (59.2)

0.110

Clinical characteristics

 Time to ED (min)

80.2 ± 66.0

87.2 ± 66.9

76.1 ± 65.4

0.218

 GCS on admission

5.9 ± 3.1

7.3 ± 3.2

5.1 ± 2.7

<0.001

 ISS on admission

24.4 ± 11.6

17.9 ± 9.8

28.4 ± 10.8

<0.001

 AIS head on admission

4.1 ± 1.1

3.5 ± 1.2

4.5 ± 0.8

<0.001

Marshall score

 I

27 (15.5)

19 (70.4)

8 (29.6)

--

 II

82 (47.1)

35 (42.7)

47 (57.3)

--

 III

13 (7.5)

3 (23.1)

10 (76.9)

--

 IV

30 (17.2)

2 (6.7)

28 (93.3)

--

 V

21 (12.1)

6 (28.6)

15 (71.4)

--

 VI

1 (0.6)

0 (0.0)

1 (100.0)

--

SBP (mmHg)

140.4 ± 32.2

140.9 ± 28.4

140.1 ± 34.6

0.861

SaO2 <92%

7 (4.0)

3 (42.9)

4 (57.1)

0.759

Mechanical ventilation

144 (82.8)

45 (31.2)

99 (68.7)

<0.001

Neurosurgery

51 (29.3)

11 (21.6)

40 (78.4)

0.006

Pupils

 Unequal

46 (26.4)

7 (10.7)

39 (35.7)

0.0005

 Unreactive

72 (41.3)

14 (21.5)

58 (53.2)

0.0001

  1. SBP and SaO2 refer to levels on admission. All data represented as either the mean ± standard deviation, or frequency (percent), where appropriate. Bold indicates p <0.05 by Student’s independent t test or chi 2, between unfavorable and favorable outcome, where appropriate
  2. Abbreviations: GOSE extended Glasgow Outcome Scale, ED Emergency Department, GCS Glasgow Coma Scale, ISS Injury Severity Score, AIS Abbreviated Injury Scores, SBP systolic blood pressure, SaO 2 oxygen saturation