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Table 1 Baseline characteristics of the study cohort

From: Catecholamines as outcome markers in isolated traumatic brain injury: the COMA-TBI study

Characteristic All patients Outcome at 6 months p value
Favorable (GOSE 5–8) Unfavorable (GOSE 1–4)
Demographics
 Frequency 174 65 (37.4) 109 (62.6) --
 Age (years) 47.5 ± 21.2 37.5 ± 16.5 53.7 ± 21.4 <0.001
 Male 130 (74.7) 53 (40.8) 77 (59.2) 0.110
Clinical characteristics
 Time to ED (min) 80.2 ± 66.0 87.2 ± 66.9 76.1 ± 65.4 0.218
 GCS on admission 5.9 ± 3.1 7.3 ± 3.2 5.1 ± 2.7 <0.001
 ISS on admission 24.4 ± 11.6 17.9 ± 9.8 28.4 ± 10.8 <0.001
 AIS head on admission 4.1 ± 1.1 3.5 ± 1.2 4.5 ± 0.8 <0.001
Marshall score
 I 27 (15.5) 19 (70.4) 8 (29.6) --
 II 82 (47.1) 35 (42.7) 47 (57.3) --
 III 13 (7.5) 3 (23.1) 10 (76.9) --
 IV 30 (17.2) 2 (6.7) 28 (93.3) --
 V 21 (12.1) 6 (28.6) 15 (71.4) --
 VI 1 (0.6) 0 (0.0) 1 (100.0) --
SBP (mmHg) 140.4 ± 32.2 140.9 ± 28.4 140.1 ± 34.6 0.861
SaO2 <92% 7 (4.0) 3 (42.9) 4 (57.1) 0.759
Mechanical ventilation 144 (82.8) 45 (31.2) 99 (68.7) <0.001
Neurosurgery 51 (29.3) 11 (21.6) 40 (78.4) 0.006
Pupils
 Unequal 46 (26.4) 7 (10.7) 39 (35.7) 0.0005
 Unreactive 72 (41.3) 14 (21.5) 58 (53.2) 0.0001
  1. SBP and SaO2 refer to levels on admission. All data represented as either the mean ± standard deviation, or frequency (percent), where appropriate. Bold indicates p <0.05 by Student’s independent t test or chi 2, between unfavorable and favorable outcome, where appropriate
  2. Abbreviations: GOSE extended Glasgow Outcome Scale, ED Emergency Department, GCS Glasgow Coma Scale, ISS Injury Severity Score, AIS Abbreviated Injury Scores, SBP systolic blood pressure, SaO 2 oxygen saturation