From: Catecholamines as outcome markers in isolated traumatic brain injury: the COMA-TBI study
Characteristic | All patients | Outcome at 6 months | p value | |
---|---|---|---|---|
Favorable (GOSE 5–8) | Unfavorable (GOSE 1–4) | |||
Demographics | ||||
Frequency | 174 | 65 (37.4) | 109 (62.6) | -- |
Age (years) | 47.5 ± 21.2 | 37.5 ± 16.5 | 53.7 ± 21.4 | <0.001 |
Male | 130 (74.7) | 53 (40.8) | 77 (59.2) | 0.110 |
Clinical characteristics | ||||
Time to ED (min) | 80.2 ± 66.0 | 87.2 ± 66.9 | 76.1 ± 65.4 | 0.218 |
GCS on admission | 5.9 ± 3.1 | 7.3 ± 3.2 | 5.1 ± 2.7 | <0.001 |
ISS on admission | 24.4 ± 11.6 | 17.9 ± 9.8 | 28.4 ± 10.8 | <0.001 |
AIS head on admission | 4.1 ± 1.1 | 3.5 ± 1.2 | 4.5 ± 0.8 | <0.001 |
Marshall score | ||||
I | 27 (15.5) | 19 (70.4) | 8 (29.6) | -- |
II | 82 (47.1) | 35 (42.7) | 47 (57.3) | -- |
III | 13 (7.5) | 3 (23.1) | 10 (76.9) | -- |
IV | 30 (17.2) | 2 (6.7) | 28 (93.3) | -- |
V | 21 (12.1) | 6 (28.6) | 15 (71.4) | -- |
VI | 1 (0.6) | 0 (0.0) | 1 (100.0) | -- |
SBP (mmHg) | 140.4 ± 32.2 | 140.9 ± 28.4 | 140.1 ± 34.6 | 0.861 |
SaO2 <92% | 7 (4.0) | 3 (42.9) | 4 (57.1) | 0.759 |
Mechanical ventilation | 144 (82.8) | 45 (31.2) | 99 (68.7) | <0.001 |
Neurosurgery | 51 (29.3) | 11 (21.6) | 40 (78.4) | 0.006 |
Pupils | ||||
Unequal | 46 (26.4) | 7 (10.7) | 39 (35.7) | 0.0005 |
Unreactive | 72 (41.3) | 14 (21.5) | 58 (53.2) | 0.0001 |