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Table 3 Diagnostic accuracy of Hemochron® Signature POCT for dabigatran

From: Point-of-care testing for emergency assessment of coagulation in patients treated with direct oral anticoagulants

Coagulation test result

Threshold (ng/mL)

Specificity (%)

Sensitivity (%)

LR

PPV (%)

NPV (%)

POCT PT ≤1.1

<30

99 (92–100)

47 (37–58)

34.6

98

59

POCT PT ≤1.2

<50

98 (88–100)

66 (56–74)

33.5

99

56

POCT ACT+ ≤100 s

<30

96 (87–99)

36 (26–47)

8.7

92

54

POCT ACT+ ≤100 s

<50

98 (88–100)

31 (23–40)

15.7

97

61

  1. n = 168 samples
  2. Sensitivity and specificity are provided with 95% confidence intervals
  3. ACT+ activated clotting time plus, LR likelihood ratio, NPV negative predictive value, POCT point of care test, PPV positive predictive value, PT prothrombin time