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Table 3 Diagnostic accuracy of Hemochron® Signature POCT for dabigatran

From: Point-of-care testing for emergency assessment of coagulation in patients treated with direct oral anticoagulants

Coagulation test result Threshold (ng/mL) Specificity (%) Sensitivity (%) LR PPV (%) NPV (%)
POCT PT ≤1.1 <30 99 (92–100) 47 (37–58) 34.6 98 59
POCT PT ≤1.2 <50 98 (88–100) 66 (56–74) 33.5 99 56
POCT ACT+ ≤100 s <30 96 (87–99) 36 (26–47) 8.7 92 54
POCT ACT+ ≤100 s <50 98 (88–100) 31 (23–40) 15.7 97 61
  1. n = 168 samples
  2. Sensitivity and specificity are provided with 95% confidence intervals
  3. ACT+ activated clotting time plus, LR likelihood ratio, NPV negative predictive value, POCT point of care test, PPV positive predictive value, PT prothrombin time