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Table 2 Diagnostic accuracy of Hemochron® Signature POCT for rivaroxaban

From: Point-of-care testing for emergency assessment of coagulation in patients treated with direct oral anticoagulants

Coagulation test result

Threshold (ng/mL)

Specificity (%)

Sensitivity (%)

LR

PPV (%)

NPV (%)

POCT PT ≤1.0

<30

97 (89–100)

33 (20–48)

11.6

88

69

POCT PT ≤1.1

<100

96 (85–99)

38 (27–50)

9.0

93

52

POCT ACT+ ≤120 s

<30

96 (87–99)

67 (52–80)

15.7

91

82

POCT ACT+ ≤130 s

<100

96 (85–99)

68 (55–78)

16.2

96

68

  1. n = 118 samples
  2. Sensitivity and specificity are provided with 95% confidence intervals
  3. ACT+ activated clotting time plus, LR likelihood ratio, NPV negative predictive value, POCT point of care test, PPV positive predictive value, PT prothrombin time
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Critical Care

ISSN: 1364-8535