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Table 1 The baseline data for patients with septic shock who were enrolled in this study

From: Use of stepwise lactate kinetics-oriented hemodynamic therapy could improve the clinical outcomes of patients with sepsis-associated hyperlactatemia

 

Lactate kinetics group

ScvO2 group

P value

n = 180

n = 180

Sex, male/female, n

95/85

106/74

0.289

Age, years

56 (44–66)

56 (40–67)

0.455

APACHE II score

18 (14–30)

20 (14–31)

0.512

WBC counts, ×10^9/L

12.9 (8.4–17.9)

12.0 (8.4–17.3)

0.957

Hemoglobin, g/L

101 (86–117)

105 (85–119)

0.217

Platelets, ×10^9/L

143 (85–191)

125 (74–196)

0.798

PT, s

15.4 (13.3–18.0)

15.1 (13.0–17.7)

0.547

APTT, s

36.2 (28.8–51.9)

35.6 (29.4–51.1)

0.519

ALT, U/L

106.0 (53.5–156.5)

78.0 (46.0–142.0)

0.161

TBIL, mmol/L

19.5 (11.6–37.2)

18.1 (10.7–41.9)

0.807

Albumin, g/L

27 (22–30)

27 (23–31)

0.109

sCR, mmol/dL

91.5 (65.3–163.5)

102 (65.5–182.5)

0.484

cTnI, mg/L)

0.42 (0.04–3.40)

0.29 (0.05–2.97)

0.635

HR, bpm

109 ± 25

114 ± 28

0.184

MAP, mmHg

83 (72–93)

87 (76–100)

0.113

Arterial lactate, mmol/L

5.8 (4.4–8.7)

5.6 (4.3–8.1)

0.156

Site of infection

 Lung, n

87

86

0.916

 Intraperitoneal, n

58

60

0.822

 Urinary system, n

1

1

1

 Biliary tract infection, n

8

10

0.629

 Skin and soft tissue, n

9

6

0.435

 Blood infection, n

9

7

0.609

 Other, n

8

10

0.629

  1. ScvO 2 central venous oxygen saturation, APACHE Acute Physiology and Chronic Health Evaluation, WBC white blood cells, PT prothrombin time, APTT activated partial thromboplastin time, ALT alanine transaminase, TBIL total bilirubin, sCR serum creatinine, cTnI cardiac troponin I, HR heart rate, MAP mean arterial pressure