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Fig. 3 | Critical Care

Fig. 3

From: SOFA and mortality endpoints in randomized controlled trials: a systematic review and meta-regression analysis

Fig. 3

Regression analyses of the relationship between the RCT treatment effects on mortality vs. (a) any SOFA endpoint, (b) Fixed-day SOFA, and (c) Delta SOFA. The size of the circle is proportional to the RCT sample size. RCTs in the green quadrants show agreement between SOFA and the effects on mortality (e.g. lower SOFA and lower mortality), while RCTs in the red quadrants show conflicting effects (lower SOFA but higher mortality or vice versa). Broken line significant association with residual heterogeneity; solid line significant association without residual heterogeneity. SOFA sequential organ failure assessment, RCT randomized controlled trial, OR odds ratio

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Critical Care

ISSN: 1364-8535