Table 1 Baseline characteristics of comatose patients who underwent brain CT scans after ECPR

Age, years (median (IQR))

41.0 (32.0–70.5)

52.0 (43.0–60.5)

51.0 (34.0–65.0)

0.503

Gender, male (n (%))

14 (73.7)

15 (65.2)

29 (31.0)

0.739

Body mass index (kg/m²)

23.1 (21.1–25.7)

24.1 (22.2–28.5)

23.6 (21.5–26.7)

0.105

 Diabetes mellitus

1 (5.3)

10 (43.5)

11 (26.2)

0.005

 Hypertension

3 (15.8)

11 (47.8)

14 (33.3)

0.048

 Malignancy

3 (15.8)

5 (21.7)

8 (19.0)

0.709

 Smoking

7 (36.8)

11 (47.8)

18 (42.9)

0.474

 Previous myocardial infarction

0 (0)

2 (8.7)

2 (4.8)

0.492

Initial Glasgow Coma Scale (median (IQR))

3 (3–6)

3 (3–4)

3 (3–5)

0.518

Target temperature manage by surface cooling device (n (%))

7 (36.8)

9 (39.1)

16 (38.1)

0.879

Interval between ECPR and CT scan (n (%))

0.001

 0–6 h

8 (42.1)

11 (47.8)

19 (45.2)

 6–12 h

0 (0)

2 (8.7)

2 (4.8)

 12–24 h

10 (52.6)

1 (4.3)

11 (26.2)

 24–48 h

1 (5.3)

9 (39.1)

10 (23.8)

 Initial lactate (mg/dl)

83.8 (51.4–127.0)

105.4 (85.6–136.9)

97.3 (68.5–132.4)

0.133

 (mmol/l)

9.3 (5.7–14.1)

11.7 (9.5–15.2)

10.8 (7.6–14.7)

 Hemoglobin before ECPR (g/dl)

13.9 (10.5–15.6)

12.0 (11.0–14.0)

12.6 (10.9–14.6)

0.263

 (mmol/l)

8.6 (6.5–9.7)

7.4 (6.8–8.7)

7.8 (6.8–9.1)

 Hemoglobin after ECPR (g/dl)

10.5 (8.8–11.9)

9.9 (8.8–11.1)

10.2 (8.8–11.5)

0.597

 (mmol/l)

6.5 (5.5–7.4)

6.1 (5.5–6.9)

6.3 (5.5–7.1)

 Total bilirubin (mg/dl)

0.7 (0.5–1.2)

1.0 (0.5–1.2)

0.8 (0.5–1.2)

0.744

 (μmol/l)

12.0 (8.6–20.5)

17.1 (8.6–20.5)

13.7 (8.6–20.5)

 Blood urea nitrogen (mg/dl)

16.7 (14.7–23.0)

17.2 (13.6–21.8)

16.7 (14.0–22.4)

0.745

 (mmol/l)

6.0 (5.2–8.2)

6.1 (4.9–7.8)

6.0 (5.0–8.0)

 Creatinine (mg/dl)

1.2 (1.0–2.0)

1.3 (1.1–1.7)

1.3 (1.1–1.8)

0.533

 (μmol/l)

106.1 (88.4–176.8)

114.9 (97.2–150.3)

114.9 (97.2–159.1)