Table 7 SOFA score on days 0 (baseline), 7, and 14 (safety population)
From: A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients
SOFA score | Parameter | IC43 100 μg with adj (N = 104) | IC43 100 μg w/o adj (N = 98) | IC43 200 μg with adj (N = 101) | Placebo (N = 98) |
|---|---|---|---|---|---|
Day 0 | n | 104 | 98 | 101 | 98 |
(baseline) | Mean (SD) | 8.6 (3.5) | 7.8 (3.5) | 8.0 (3.2) | 8.7 (3.7) |
Median | 8.0 | 8.0 | 8.0 | 9.0 | |
Day 7 | n | 88 | 79 | 78 | 79 |
Mean (SD) | 6.3 (4.1) | 5.9 (4.1) | 5.9 (3.6) | 6.7 (4.5) | |
Median | 6.0 | 5.0 | 6.0 | 5.0 | |
Day 14 | n | 61 | 48 | 49 | 50 |
Mean (SD) | 5.6 (3.8) | 6.2 (4.1) | 7.1 (4.5) | 5.5 (4.7) | |
Median | 5.0 | 5.5 | 6.0 | 4.0 |