Skip to main content

Table 7 SOFA score on days 0 (baseline), 7, and 14 (safety population)

From: A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients

SOFA score Parameter IC43 100 μg with adj
(N = 104)
IC43 100 μg w/o adj
(N = 98)
IC43 200 μg with adj
(N = 101)
Placebo
(N = 98)
Day 0 n 104 98 101 98
(baseline) Mean (SD) 8.6 (3.5) 7.8 (3.5) 8.0 (3.2) 8.7 (3.7)
  Median 8.0 8.0 8.0 9.0
Day 7 n 88 79 78 79
  Mean (SD) 6.3 (4.1) 5.9 (4.1) 5.9 (3.6) 6.7 (4.5)
  Median 6.0 5.0 6.0 5.0
Day 14 n 61 48 49 50
  Mean (SD) 5.6 (3.8) 6.2 (4.1) 7.1 (4.5) 5.5 (4.7)
  Median 5.0 5.5 6.0 4.0
  1. n number of patients, SD standard deviation, SOFA sequential organ failure assessment, w/o adj without aluminum hydroxide adjuvant, with adj with aluminum hydroxide adjuvant