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Table 2 Respiratory mechanics for the patients during mechanical ventilation at various tidal volumes (\( \overline{\mathrm{x}} \) ± s, n = 19)

From: The effects of low tidal ventilation on lung strain correlate with respiratory system compliance

 

VT (ml/kg)

 

6

8

10

12

PEEPtot, cmH2O

 C ≥ 0.6 (n = 9)

8.3 ± 1.6

8.3 ± 1.6

8.3 ± 1.6

8.1 ± 1.6

 C < 0.6 (n = 10)

8.1 ± 1.9

8.1 ± 2.0

8.1 ± 2.0

8.1 ± 2.0

Ppeak, cmH2O

 C ≥ 0.6 (n = 9)

20.1 ± 4.4

24.4 ± 4.0

31.3 ± 5.7*

34.9 ± 4.9*

 C < 0.6 (n = 10)

27.1 ± 3.9

31.0 ± 4.9#

33.9 ± 4.9*

35.6 ± 5.3*

Pplat, cmH2O

 C ≥ 0.6 (n = 9)

15.7 ± 2.5

19.3 ± 2.5*

22.3 ± 3.1*

24.4 ± 2.3*

 C < 0.6 (n = 10)

21.8 ± 2.6#

25.6 ± 4.1#

26.7 ± 3.2*#

27.6 ± 2.6*#

Pmean, cmH2O

 C ≥ 0.6 (n = 9)

10.1 ± 2.5

11.1 ± 2.0

12.6 ± 2.4

13.0 ± 2.1

 C < 0.6 (n = 10)

12.6 ± 3.5

14.3 ± 4.9

14.6 ± 4.9

14.8 ± 4.8

EELV, ml

 C ≥ 0.6 (n = 9)

2804 ± 1562

2717 ± 1124

2628 ± 1086

2534 ± 1048

 C < 0.6 (n = 10)

1317 ± 775#

1347 ± 886#

1485 ± 840#

1482 ± 1230

C, ml/(cmH2O/kg)

 C ≥ 0.6 (n = 9)

0.85 ± 0.23

0.75 ± 0.14

0.70 ± 0.11

0.73 ± 0.10

 C < 0.6 (n = 10)

0.45 ± 0.08#

0.40 ± 0.16#

0.48 ± 0.10#

0.47 ± 0.09#

  1. Abbreviations: V T tidal volume PEEPtot total positive-end expiratory pressure, Ppeak peak airway pressure, Pplat plateau pressure, Pmean mean airway pressure, EELV end-expiratory lung volume, C respiratory system compliance
  2. # p < 0.05 for the comparison with C ≥ 0.6 subjects
  3. * p <0.05 for the comparison with VT = 6 ml/kg PBW