Table 1 Characteristics of patients with and without platelet (PLT) transfusion in the ICU

Age, years, mean (SD)

60 (18)

59 (17)

60 (17)

0.04

Gender, male, n (%)

12 086 (63.7%)

1 511 (67.2%)

10 575 (63.3%)

<0.01

APACHE III score, mean (SD)

54 (26)

65 (29)

52 (25)

<0.01

 Any known comorbidity

3 838 (20%)

702 (31%)

3 136 (19%)

<0.01

 Cancer^a

857 (4.5%)

192 (8.5%)

665 (4.0%)

<0.01

 Hepatic disease^b

674 (3.6%)

216 (9.6%)

458 (2.7%)

<0.01

 Immunocompromised^c

1 180 (6.2%)

311 (13.8%)

869 (5.2%)

<0.01

 IDDM

511 (2.7%)

60 (2.7%)

451 (2.7%)

0.93

 Chronic respiratory disease

840 (4.4%)

92 (4.1%)

748 (4.5%)

0.40

 CVD

754 (4%)

137 (6.1%)

617 (3.7%)

<0.01

 Chronic renal failure

422 (2%)

59 (2.6%)

363 (2.2%)

0.17

 Cardiovascular

5 161 (27%)

701 (31%)

4 460 (27%)

<0.01

 Gastrointestinal

3 595 (19%)

581 (26%)

3 014 (18%)

<0.01

 Haematological

152 (0.8%)

96 (4.3%)

56 (0.3%)

<0.01

 Neurological

1 586 (8.4%)

108 (4.8%)

1 478 (8.8%)

<0.01

 Renal/genitourinary

1 017 (5.4%)

108 (4.8%)

909 (5.4%)

0.2

 Respiratory

1 467 (7.7%)

127 (5.6%)

1 340 (8%)

<0.01

 Sepsis

503 (2.7%)

73 (3.2%)

430 (2.6%)

0.06

 Other^d

2 815 (14.8%)

82 (3.6%)

2 733 (16.4%)

<0.01

 Trauma

2 669 (14.1%)

374 (16.6%)

2 295 (13.7%)

<0.01

Requirement for MV

11 531 (61%)

1 952 (87%)

9 579 (57%)

<0.01

Requirement for RRT

1 135 (6%)

449 (20%)

686 (4%)

<0.01