Fig. 3
From: Effects of low doses of esmolol on cardiac and vascular function in experimental septic shock
Western blot analysis of protein expression in the heart. Western blots revealing phosphorylated AKT (p-AKT) (a), phosphorylated endothelial nitric oxide synthase (p-eNOS) (b), nuclear factor - κB (NF-κB) (c), nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IκBα) (d) and inducible nitric oxide synthase (iNOS) (e). Proteins were obtained from heart lysates (n = 8) prepared from all experimental rat groups. A typical western blot is shown below each histogram. Densitometric analysis (n = 8) was used to calculate the normalized protein ratio. Data are expressed as median ± interquartile range. Upper edges of error bars represent the 75th percentile in each group. *p < 0.05. CLP cecal ligation and puncture, E-1 esmolol 1 mg.kg−1.h−1, E-5 esmolol 5 mg.kg−1.h−1, E-18 esmolol 18 mg.kg−1.h−1