Fig. 1

Study protocol and visual presentation of study execution. a Visualization of study protocol. Intervention started with 10 minutes of resting, followed by 6 minutes of physiotherapy (passive range of motion of upper and lower extremity). After physiotherapy there was a short resting time, followed by WBV. After WBV, a long resting period took place. Serum blood samples and blood gas analyses were performed at different time points, as shown. Longitudinal analysis of intervals was performed at five different time segments. Analysis was performed at baseline, at physiotherapy, during WBV, and at early and late rest periods. b Female patient in a supine position. Vibration device positioned at the end of the bed, with the patient’s feet placed on the middle of the device. An elastic strap is placed around the knee joint to generate pressure on the vibration device. The aim was to flex the knee joint about 20°. The physiotherapist assisted in the stabilization of the lower extremities if necessary. WBV whole-body vibration