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Table 1 Studies relating long-term outcomes after ECMO for severe ARDS

From: Outcomes and survival prediction models for severe adult acute respiratory distress syndrome treated with extracorporeal membrane oxygenation

Study

Cohort enrolment

Total population

Follow-up

Primary outcome

Long-term outcomes

population

Median time

Peek et al.[4]

2001–2006

68

52

6 months

Death or severe disability at 6 months

Lung function evaluated with PFT, overall health status, HRQoL, depression and anxiety symptoms

Lindén et al.[29]

Before 2009

37

21

26 (12–50) months

Pulmonary morphology (CT scan)

Lung function (PFT), pulmonary symptoms (SGRQ)

Hodgson et al.[33]

2009–2011

34

15

9 (8–19) months

HRQoL (SF-36)

Related ECMO complications, survival, discharge destination, return-to-work status

Luyt et al.[31]

Winter 2009

67

12

12 months

HRQoL (SF-36)

Symptoms and activities since hospital discharge, weight and muscle-strength testing, lung morphology (CT scan), anxiety and depression (HAD scale), symptoms of PTSD (IES)

Schmidt et al.[6]

2008–2012

140

67

17 (11–28) months

Factors associated with death at 6 months

HRQoL (SF-36 score), pulmonary symptoms (SGRQ), anxiety and depression (HAD scale), symptoms of PTSD (IES)

Li et al.[30]

2009–2012

29

8

12 months

Pulmonary morphology

  1. ARDS acute respiratory distress syndrome, ECMO extracorporeal membrane oxygenation, HAD hospital anxiety and depression, HRQoL health-related quality of life, IES Impact of Event Scale, PFT pulmonary function tests, PTSD post-traumatic stress disorder, SF-36 Medical Outcome Short-Form, SGRQ St George’s Respiratory Questionnaire