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Table 4 Logistic and linear regression: association between skeletal muscle density or intermuscular adipose tissue and secondary outcomes

From: Skeletal muscle quality as assessed by CT-derived skeletal muscle density is associated with 6-month mortality in mechanically ventilated critically ill patients

  Univariable Model 2 Model 3
  OR/B 95% CI P value OR/B 95% CI P value OR/B 95% CI P value
Discharge to home          
 SMD (per 10 HU) 1.039 0.864 to 1.250 0.683 0.990 0.816 to 1.200 0.915 0.926 0.718 to 1.195 0.556
 IMAT (per 10 cm2) 0.886 0.741 to 1.059 0.182 0.912 0.761 to 1.093 0.317 0.884 0.715 to 1.093 0.254
Length of ventilation          
 SMD (per 10 HU) –0.038 –0.107 to 0.032 0.292 –0.003 –0.075 to 0.069 0.936 –0.018 –0.111 to 0.075 0.705
 IMAT (per 10 cm2) 0.050 –0.014 to 0.115 0.126 0.029 –0.036 to 0.094 0.384 0.026 –0.049 to 0.101 0.499
Length of ICU stay          
 SMD (per 10 HU) –0.051 –0.123 to 0.020 0.158 –0.020 –0.092 to 0.053 0.598 –0.032 –0.128 to 0.063 0.506
 IMAT (per 10 cm2) 0.064 –0.003 to 0.130 0.059 0.043 –0.023 to 0.110 0.199 0.041 –0.036 to 0.119 0.292
Length of hospital stay          
 SMD (per 10 HU) –0.123 –0.192 to –0.054 0.001 –0.112 –0.184 to –0.041 0.002 –0.134 –0.228 to –0.040 0.005
 IMAT (per 10 cm2) 0.075 0.010 to 0.140 0.023 0.065 –0.001 to 0.131 0.052 0.064 –0.012 to 0.141 0.100
  1. Model 2: adjusted for APACHE II score
  2. Model 3: adjusted for APACHE II score, skeletal muscle area, and BMI
  3. Discharge to home results are given as OR; length of ventilation, ICU, and hospital stay are given as B values
  4. Values in bold indicate statistically significant p values
  5. APACHE Acute Physiological, Age, and Chronic Health Evaluation, B beta coefficient, CI confidence interval, HU Hounsfield Units, ICU intensive care unit, IMAT intermuscular adipose tissue, OR odds ratio, SMD skeletal muscle density