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Table 3 Cox regression: association between skeletal muscle density or intermuscular adipose tissue and mortality

From: Skeletal muscle quality as assessed by CT-derived skeletal muscle density is associated with 6-month mortality in mechanically ventilated critically ill patients

  Univariable
N = 491
Model 2
N = 491
Model 3
N = 491
Model 4
(n = 337)
6-month mortality HR 95% CI P value HR 95% CI P value HR 95% CI P value HR 95% CI P value
SMD (per 10 HU) 0.640 0.552–0.742 <0.001 0.703 0.605–0.818 <0.001 0.774 0.643–0.931 0.006 0.728 0.571–0.928 0.010
IMAT (per 10 cm2) 1.153 1.042–1.277 0.006 1.092 0.980–1.217 0.110 1.092 0.966–1.236 0.159 1.244 1.048–1.476 0.012
  1. Model 2: adjusted for APACHE II score
  2. Model 3: adjusted for APACHE II score, skeletal muscle area, and BMI
  3. Model 4 (subgroup analysis): adjusted for APACHE II score, skeletal muscle area, visceral adipose tissue, and subcutaneous adipose tissue
  4. Values in bold indicate statistically significant p values
  5. APACHE Acute Physiological, Age, and Chronic Health Evaluation, CI confidence interval, HR hazard ratio, HU Hounsfield Units, IMAT intermuscular adipose tissue, SMD skeletal muscle density