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Table 2 Relative risk, baseline risk, risk with treatment, absolute risk reduction, and number needed to treat

From: Chlorhexidine bathing and health care-associated infections among adult intensive care patients: a systematic review and meta-analysis

Outcome

Relative effect (95% CrI)

Median (IQR) baseline risk per 1000 days

Risk difference per 1000 days (95% CrI)

Number needed to treat

BSI

0.78 (0.45, 1.03)

5 (4–6)

1.1 (3 fewer to 0.1 more)

910

CLABSI

0.44 (0.26, 0.75)a

5 (3–9)

2.8 (4 fewer to 1.2 fewer)a

360

VAP

0.82 (0.57, 1.25)

10 (5–16)

1.8 (4 fewer to 3 more)

560

CAUTI

0.93 (0.45, 1.66)

8 (2–14)

0.56 (5 fewer to 5 more)

1565

MRSA-C

0.59 (0.36, 0.94)a

4 (3–22)

1.64 (3 fewer to 0.2 fewer)a

595

MRSA-B

0.64 (0.43, 0.91)a

1 (0.2–2)

0.36 (0.6 fewer to 0.1 fewer)a

2780

VRE-C

0.53 (0.20, 1.55)

5 (4–15)

2.35 (4 fewer to 3 more)

425

VRE-B

0.53 (0.15, 2.26)

1 (0.5–2)

0.47 (0.9 fewer to 1.3 more)

2130

C-diff

0.93 (0.48, 1.80)

1 (0.5–3)

0.07 (0.5 fewer to 0.8 more)

14,290

  1. aEstimates with 95% CrI excluding the null (1 for IRR)
  2. IRR incidence rate ratio, CrI credible interval from Bayesian models, BSI bloodstream infection, CAUTI catheter-associated urinary tract infections, C-diff Clostridium Difficile, CLABSI central line-associated bloodstream infection, MRSA methicillin-resistant Staphylococcus aureus, MRSA-C MRSA colonisation, MRSA-B MRSA-associated BSI, VAP ventilator-associated pneumonia, VRE vancomycin-resistant Enterococcus, VRE-C VRE colonisation, VRE-B VRE-associated BSI