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Table 2 Efficacy of the intravascular versus surface devices during induction and maintenance/rewarming phases

From: Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest – an analysis of the TTM trial data

Performance metric Intravascular Surface device p value
Induction (33 °C group; n = 195); 52 intravascular versus 143 surface)
Time to target temperature (minutes) 210 [180] 240 [180] 0.58
Maximum cooling rate in induction phase (°C/hour) 1 [0.7] 1 [0.9] 0.44
Number of patients achieving target temperature in 4 hours 34, 65% 86, 60% 0.30
Number of patients achieving target temperature ever 52, [100] 140, [97] 0.47
Episodes of overcooling 4, 8% 49, 34% 0.15
Maintenance and rewarming (33 and 36 °C groups; n = 844); 226 intravascular versus 618 surface)
Cumulative deviation out of range (°C hours) 3.2 [5.0] 9.3 [8.0] <0.001
Number of patients out of range 127, 57.0% 568, 91.5% 0.006
Time out of range (hours) 1 [4.0] 8.0 [9.0] <0.001
Number of patients with temperature ≥37.5 °C 33 °C 4, 3% 41, 12% 0.44
36 °C 27, 23% 153, 47% 0.99
  1. Values are n,% or median [IQR] as appropriate