Performance metric | Intravascular | Surface device | p value | |
---|---|---|---|---|
Induction (33 °C group; n = 195); 52 intravascular versus 143 surface) | ||||
Time to target temperature (minutes) | 210 [180] | 240 [180] | 0.58 | |
Maximum cooling rate in induction phase (°C/hour) | 1 [0.7] | 1 [0.9] | 0.44 | |
Number of patients achieving target temperature in 4 hours | 34, 65% | 86, 60% | 0.30 | |
Number of patients achieving target temperature ever | 52, [100] | 140, [97] | 0.47 | |
Episodes of overcooling | 4, 8% | 49, 34% | 0.15 | |
Maintenance and rewarming (33 and 36 °C groups; n = 844); 226 intravascular versus 618 surface) | ||||
Cumulative deviation out of range (°C hours) | 3.2 [5.0] | 9.3 [8.0] | <0.001 | |
Number of patients out of range | 127, 57.0% | 568, 91.5% | 0.006 | |
Time out of range (hours) | 1 [4.0] | 8.0 [9.0] | <0.001 | |
Number of patients with temperature ≥37.5 °C | 33 °C | 4, 3% | 41, 12% | 0.44 |
36 °C | 27, 23% | 153, 47% | 0.99 |