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Table 3 Disease severity index of sepsis in patients with various AF statuses

From: Prognostic impact of restored sinus rhythm in patients with sepsis and new-onset atrial fibrillation

  Overall patients (n = 503) P value
No NeOAF (n = 263) NeOAF to SR (n = 165) NeOAF to AF (n = 75)
Infection site, n (%)
 Respiratory tract 168 (63.9) 112 (67.9) 48 (64.0)  
 Urinary tract 57 (21.7) 35 (21.2) 14 (18.7)  
 Gastrointestinal 23 (8.7) 9 (5.5) 5 (6.7)  
 Others 15 (5.7) 9 (5.5) 8 (10.7)  
SOFA score 7.0 ± 3.2 7.6 ± 3.0 9.3 ± 3.2bc <0.01
APACHE II score 21.6 ± 5.5 22.8 ± 5.8 24.6 ± 6.1b <0.01
Total organ failurea, n 2 (1–3) 2 (1–3) 3 (2–4)  
 Neurologic failure 87 (33.1) 49 (29.7) 39 (52.0)bc <0.01
 Circulatory failure 118 (44.9) 82 (49.7) 57 (76.0)bc <0.01
 Respiratory failure 229 (87.1) 150 (90.9) 71 (94.7) 0.13
 Hepatic failure 8 (3.0) 4 (2.4) 8 (10.7)bc <0.01
 Renal failure 86 (32.7) 65 (39.4) 39 (52.0)b <0.01
 Hematologic failure 9 (3.4) 5 (3.0) 4 (5.3) 0.66
Vasopressor use, n (%)
 Dopamine use 95 (36.3) 64 (38.8) 49 (65.3)bc <0.01
 Norepinephrine use 80 (30.4) 58 (35.2) 48 (64.0)bc <0.01
Intervention, n (%)
 Ventilator use 221 (84.0) 143 (86.7) 69 (92.0) 0.21
 New-onset dialysis 50 (19.0) 35 (21.2) 19 (25.3) 0.48
  1. NeOAF new-onset atrial fibrillation, AF atrial fibrillation, SR sinus rhythm SOFA Sequential Organ Failure Assessment score, APACHE II Acute Physiology and Chronic Health Evaluation II. aTotal organ failure is presented as median and interquartile range. b P < 0.05 vs. no NeOAF. c P < 0.05 vs. NeOAF to SR