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Table 6 Adjusted relative risk for in-hospital mortality within KDIGO acute kidney injury stage by trajectory of acute kidney injury within group 2

From: Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death

KDIGO AKI stage AKI Subphenotype n (%) Deaths, n (%) RRa (95% CI)
No AKI 573 (31) 62 (10.8)  
Stage 1 Resolving 610 (33) 70 (11.5) 1.0 (reference)
Nonresolving 334 (17) 78 (23.4) 2.06 (1.52–2.80)
Stage 2 Resolving 131 (7) 21 (16.0) 1.0 (reference)
Nonresolving 34 (2) 14 (41.2) 2.41 (1.36–4.29)
Stage 3 Resolving 134 (7) 24 (17.9) 1.0 (reference)
Nonresolving 51 (3) 15 (29.4) 1.59 (0.87–2.92)
  1. AKI Acute kidney injury, KDIGO Kidney Disease: Improving Global Outcomes, RR Relative risk
  2. p for interaction between KDIGO stage and trajectory on risk of death: p = 0.035
  3. a Adjusted for age, sex, race (all white), body mass index, diabetes mellitus, Sepsis-related Organ Failure Assessment without renal component, vasopressors, sepsis