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Table 2 Patient characteristics in group 2 (mixed medical-surgical)

From: Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death

Clinical variables No acute kidney injury Acute kidney injury Total AKI versus no AKI p value
Total 573 1294 1867  
Baseline demographics
 Age, years 56.8 ± 16.8 59.8 ± 18 58.9 ± 18 <0.01
 Male sex, n (%) 246 (43) 543 (42) 794 (43) 0.78
 Body mass index, kg/m2 27.5 ± 7.7 28.2 ± 7.5 27.9 ± 7.6 0.09
Race, n (%)
 White 573 (100) 1294 (100) 1867 (100) 1
Comorbidities, n (%)
 Diabetes mellitus 95 (17) 331 (26) 426 (23) <0.01
 SOFA score 7.0 ± 2.3 8.8 ± 2.9 8.3 ± 2.8 <0.01
 SOFA without renal component 6.9 ± 2.2 7.7 ± 2.5 7.5 ± 2.5 <0.01
 APACHE III score 64 ± 24.6 78 ± 26.8 74 ± 26.8 <0.01
ICU events, n (%)
 Mechanical ventilation 416 (78) 909 (70) 1325 (77) <0.01
 Sepsis 325 (56) 877 (68) 1202 (64) <0.01
 Vasopressors 134 (35) 571 (44) 705 (48) <0.01
 Diagnosis of ARDS 306 (53) 700 (37) 1006 (54) <0.01
Clinical risk for ARDS, n (%)
 Pneumonia 298 (52) 702 (54) 1000 (54) 0.37
 Sepsis 366 (64) 1006 (78) 1372 (73) <0.01
 Aspiration 74 (13) 158 (12) 232 (12) 0.75
 Trauma 57 (10) 86 (7) 143 (8) 0.01
 Other 23 (4) 31 (2) 54 (3) 0.06
Admission status, n (%)
 Direct 518 (90) 1192 (92) 1710 (92) 0.21
 Transfer 55 (10) 102 (8) 157 (8)  
KDIGO stage of acute kidney injury, n (%)
 Stage 0 573 (100) 0 573 (31)  
 Stage 1 0 944 (73) 944 (51)  
 Stage 2 0 165 (13) 165 (9)  
 Stage 3 0 185 (14) 185 (10)  
  1. Abbreviations: AKI Acute kidney injury, APACHE III Acute Physiology and Chronic Health Evaluation III, ARDS Acute respiratory distress syndrome, ICU Intensive care unit, KDIGO Kidney Disease: Improving Global Outcomes, SOFA Sepsis-related Organ Failure Assessment
  2. Data shown as mean ± standard deviation, n (%) as appropriate