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Table 2 Patient characteristics in group 2 (mixed medical-surgical)

From: Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death

Clinical variables

No acute kidney injury

Acute kidney injury

Total

AKI versus no AKI p value

Total

573

1294

1867

 

Baseline demographics

 Age, years

56.8 ± 16.8

59.8 ± 18

58.9 ± 18

<0.01

 Male sex, n (%)

246 (43)

543 (42)

794 (43)

0.78

 Body mass index, kg/m2

27.5 ± 7.7

28.2 ± 7.5

27.9 ± 7.6

0.09

Race, n (%)

 White

573 (100)

1294 (100)

1867 (100)

1

Comorbidities, n (%)

 Diabetes mellitus

95 (17)

331 (26)

426 (23)

<0.01

 SOFA score

7.0 ± 2.3

8.8 ± 2.9

8.3 ± 2.8

<0.01

 SOFA without renal component

6.9 ± 2.2

7.7 ± 2.5

7.5 ± 2.5

<0.01

 APACHE III score

64 ± 24.6

78 ± 26.8

74 ± 26.8

<0.01

ICU events, n (%)

 Mechanical ventilation

416 (78)

909 (70)

1325 (77)

<0.01

 Sepsis

325 (56)

877 (68)

1202 (64)

<0.01

 Vasopressors

134 (35)

571 (44)

705 (48)

<0.01

 Diagnosis of ARDS

306 (53)

700 (37)

1006 (54)

<0.01

Clinical risk for ARDS, n (%)

 Pneumonia

298 (52)

702 (54)

1000 (54)

0.37

 Sepsis

366 (64)

1006 (78)

1372 (73)

<0.01

 Aspiration

74 (13)

158 (12)

232 (12)

0.75

 Trauma

57 (10)

86 (7)

143 (8)

0.01

 Other

23 (4)

31 (2)

54 (3)

0.06

Admission status, n (%)

 Direct

518 (90)

1192 (92)

1710 (92)

0.21

 Transfer

55 (10)

102 (8)

157 (8)

 

KDIGO stage of acute kidney injury, n (%)

 Stage 0

573 (100)

0

573 (31)

 

 Stage 1

0

944 (73)

944 (51)

 

 Stage 2

0

165 (13)

165 (9)

 

 Stage 3

0

185 (14)

185 (10)

 
  1. Abbreviations: AKI Acute kidney injury, APACHE III Acute Physiology and Chronic Health Evaluation III, ARDS Acute respiratory distress syndrome, ICU Intensive care unit, KDIGO Kidney Disease: Improving Global Outcomes, SOFA Sepsis-related Organ Failure Assessment
  2. Data shown as mean ± standard deviation, n (%) as appropriate