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Table 3 Organ support and outcomes in patients admitted to the ICU with suspected septic shock (n = 508) and comparison between patients with early-confirmed septic shock (EC-SS) or non-early confirmed septic shock (Non EC-SS)

From: Septic shock with no diagnosis at 24 hours: a pragmatic multicenter prospective cohort study

 

All patients (n = 508)

EC-SS (n = 374)

Non EC-SS (n = 134)

P

Tracheal intubation

397 (78)

294 (79)

103 (77)

0.67

ARDS

167 (33)

143 (38)

24 (18)

<0.0001

Renal replacement therapy

145 (28)

95 (25)

50 (37)

0.009

Steroids for septic shocka

197 (39)

143 (38)

54 (40)

0.67

ECMO

8 (2)

5 (1)

3 (2)

0.44

Duration of tracheal intubation, days

4 (1 − 9)

4 (1 − 9)

4 (0 − 6)

0.19

Duration of vasopressors support, days

3 (2 − 5)

3 (2 − 5)

3 (2 − 6)

0.55

Duration of ICU stay, days

7 (4 − 14)

7 (4 − 24)

7 (4 − 21)

0.69

ICU mortality

188 (37)

139 (37)

49 (37)

0.90

Follow-up duration, days

29 (7 − 96)

30 (8 − 91)

25 (6 − 113)

0.75

Mortality over the follow-up period

232 (46)

166 (44)

66 (49)

0.33

  1. Categorical variables are expressed as n (%) and continuous variables as median (IQR 25–75). aIncludes eight patients receiving either steroids or placebo because of clinical trial enrolment.
  2. ARDS acute respiratory distress syndrome, ECMO extra-corporeal membrane oxygenation, ICU Intensive Care Unit