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Table 6 Biological variables and electrocardiogram before and at the end of SBT

From: Cardiac dysfunction induced by weaning from mechanical ventilation: incidence, risk factors, and effects of fluid removal

    P values
  Baseline At the end of SBT (except for troponin Ic, measured at 4 h) At the end of SBT vs. baseline Succeeded SBT vs. failed SBT at baseline Succeeded SBT vs. failed SBT at the end of SBT Cases with WiPO vs. cases without WiPO at baseline Cases with WiPO vs. cases without WiPO at the end of SBT
PaCO2 (mmHg)
 Succeeded SBT (n = 155) 37 ± 7 38 ± 7      
 Failed SBT (n = 124) 40 ± 8 46 ± 17 <0.01 <0.01 <0.01   
  Cases with WiPO (n = 75) 41 ± 9 50 ± 18 <0.01     
  Cases without WiPO (n = 49) 39 ± 7 41 ± 12     0.11 0.01
PaO2 (mmHg)
 Succeeded SBT (n = 155) 105 ± 27 97 ± 37 0.03     
 Failed SBT (n = 124) 96 ± 22 72 ± 17 <0.01 <0.01 <0.01   
  Cases with WiPO (n = 75) 93 ± 17 71 ± 16 <0.01     
  Cases without WiPO (n = 49) 101 ± 27 74 ± 20 <0.01    0.05 0.52
Haemoglobin (g/dL)
 Succeeded SBT (n = 155) 9.9 ± 1.4 10.0 ± 1.5      
 Failed SBT (n = 124) 9.4 ± 1.4 10.0 ± 1.5 <0.01 <0.01 0.81   
  Cases with WiPO (n = 75) 9.1 ± 1.2 10.2 ± 1.3 <0.01     
  Cases without WiPO (n = 49) 9.7 ± 1.5 9.5 ± 1.6     0.04 0.02
Plasma protein concentration (g/L)
 Succeeded SBT (n = 155) 58 ± 11 59 ± 11 0.01     
 Failed SBT (n = 124) 55 ± 9 57 ± 9 <0.01 0.02 0.19   
  Cases with WiPO (n = 75) 53 ± 9 58 ± 10 <0.01     
  Cases without WiPO (n = 49) 58 ± 9 57 ± 8     0.00 0.60
Troponin Ic (ng/mL)
 Succeeded SBT (n = 155) 0.07 ± 0.13 0.09 ± 0.06 0.08     
 Failed SBT (n = 124) 0.10 ± 0.08 0.10 ± 0.06 1.00 0.03 0.17   
  Cases with WiPO (n = 75) 0.11 ± 0.08 0.11 ± 0.08 1.00     
  Cases without WiPO (n = 49) 0.07 ± 0.10 0.09 ± 0.09 0.30    0.02 0.20
Patients with increase in troponin Ic >0.5 ng/mL
 Succeeded SBT (n = 155) 0 (0 %)      
 Failed SBT (n = 124) 0 (0 %)      
  Cases with WiPO (n = 75) 0 (0 %)      
  Cases without WiPO (n = 49) 0 (0 %)      
Patients with changes in electrocardiogram        
 Succeeded SBT (n = 155) 5 (3 %)      
 Failed SBT (n = 124) 5 (4 %)      
  Cases with WiPO (n = 75) 4 (5 %)      
  Cases without WiPO (n = 49) 1 (2 %)      
  1. Values are expressed as mean ± standard deviation or number and frequency (%)
  2. PaO2 arterial partial pressure in oxygen , PaCO2 arterial partial pressure in carbon dioxide, SBT spontaneous breathing trial, WiPO weaning-induced pulmonary oedema