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Table 5 Haemodynamic variables before and at the end of SBT

From: Cardiac dysfunction induced by weaning from mechanical ventilation: incidence, risk factors, and effects of fluid removal

   

P values

 

Baseline

At the end of SBT

At the end of SBT vs. baseline

Succeeded SBT vs. failed SBT at baseline

Succeeded SBT vs. failed SBT at the end of SBT

Cases with WiPO vs. cases without WiPO at baseline

Cases with WiPO vs. cases without WiPO at the end of SBT

Heart rate (beats/min)

 Succeeded SBT (n = 155)

91 ± 15

93 ± 16

0.093

    

 Failed SBT (n = 124)

91 ± 15

101 ± 18

0.000

0.80

<0.01

  

  Cases with WiPO (n = 75)

89 ± 15

102 ± 18

0.000

    

  Cases without WiPO (n = 49)

93 ± 14

99 ± 17

0.011

  

0.10

0.37

Systolic arterial pressure (mmHg)

 Succeeded SBT (n = 155)

134 ± 22

136 ± 22

0.214

    

 Failed SBT (n = 124)

135 ± 23

144 ± 26

0.000

0.70

<0.01

  

  Cases with WiPO (n = 75)

138 ± 23

152 ± 26

0.000

    

  Cases without WiPO (n = 49)

130 ± 22

131 ± 22

0.716

  

0.06

<0.01

Mean arterial pressure (mmHg)

 Succeeded SBT (n = 155)

89 ± 13

88 ± 14

0.478

    

 ailed SBT (n = 124)

90 ± 15

94 ± 18

0.002

0.87

<0.01

  

  Cases with WiPO (n = 75)

92 ± 16

100 ± 18

0.000

    

  Cases without WiPO (n = 49)

87 ± 15

87 ± 15

0.983

  

0.09

<0.01

Diastolic arterial pressure (mmHg)

 Succeeded SBT (n = 155)

67 ± 11

68 ± 12

0.764

    

 Failed SBT (n = 124)

66 ± 12

69 ± 14

0.021

0.53

0.35

  

  Cases with WiPO (n = 75)

67 ± 12

72 ± 14

0.006

    

  Cases without WiPO (n = 49)

65 ± 11

65 ± 12

   

0.30

0.01

Cardiac index (L/min/m2)

 Succeeded SBT (n = 40)

3.4 ± 0.7

3.9 ± 1

0.000

    

 Failed SBT (n = 45)

3.2 ± 0.7

3.6 ± 1

0.001

0.13

0.13

  

  Cases with WiPO (n = 30)

3.2 ± 0.7

3.8 ± 1

0.000

    

  Cases without WiPO (n = 15)

3.1 ± 0.6

3.1 ± 1

1.000

  

0.79

0.02

Global end-diatolic volume (mL/m2)

 Succeeded SBT (n = 40)

825 ± 254

880 ± 177

0.199

    

 Failed SBT (n = 45)

815 ± 225

916 ± 287

0.002

0.88

0.59

  

  Cases with WiPO (n = 30)

849 ± 133

1032 ± 233

0.000

    

  Cases without WiPO (n = 15)

632 ± 166

624 ± 187

0.718

  

0.01

<0.01

Extravascular lung water (mL/kg)

 Succeeded SBT (n = 40)

10 ± 5

11 ± 3

0.874

    

 Failed SBT (n = 45)

11 ± 3

12 ± 4

0.020

0.91

0.09

  

  Cases with WiPO (n = 30)

11 ± 3

14 ± 4

0.030

    

  Cases without WiPO (n = 15)

9 ± 5

10 ± 1

0.296

  

0.05

0.01

  1. Values are expressed as mean ± standard deviation
  2. SBT spontaneous breathing trial, WiPO weaning-induced pulmonary oedema