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Table 1 Patient characteristics at inclusion

From: Cardiac dysfunction induced by weaning from mechanical ventilation: incidence, risk factors, and effects of fluid removal

 

All patients

Patients with at least one WiPO

Patients without any WiPO

P valuea

(n = 81)

(n = 29)

(n = 52)

Age (years)

62 ± 15

67 ± 12

60 ± 16

0.03

Male gender

41 (51 %)

14 (48 %)

27 (52 %)

 

Simplified Acute Physiology Score II

47 ± 18

53 ± 22

43 ± 14

0.01

Body mass index (on admission)

27 ± 8

31 ± 10

24 ± 6

<0.01

 Obesity

22 (27 %)

13 (45 %)

9 (17 %)

0.01

Aetiology of intubation

 Pneumonia

35 (43 %)

13 (45 %)

22 (42 %)

0.99

 Septic shock without pneumonia

27 (33 %)

10 (34 %)

17 (33 %)

0.93

 Coma

6 (7 %)

0 (0 %)

6 (7 %)

<0.01

 Drug poisoning of other origin

2 (2 %)

0 (0 %)

2 (2 %)

<0.01

 Neuromuscular disease

5 (6 %)

0 (0 %)

5 (10 %)

0.07

 Cardiogenic shock

4 (5 %)

4 (14 %)

0 (0 %)

0.01

 Exacerbation of COPD

2 (2 %)

2 (7 %)

0 (0 %)

0.24

Previous COPD

17 (21 %)

11 (38 %)

6 (11 %)

0.01

Previous cardiovascular diseases

 Hypertension

53 (65 %)

22 (76 %)

31 (60 %)

0.22

 Atrial fibrillation

13 (16 %)

9 (31 %)

4 (8 %)

0.01

 “Structural” cardiopathy

32 (39 %)

19 (69 %)

13 (25 %)

0.00

  Dilated cardiopathy

23 (28 %)

14(48 %)

9 (17 %)

0.00

  Hypertrophic cardiopathy

7 (4 %)

4 (3 %)

3 (4 %)

0.41

  Significant valvular disease

2 (2 %)

1 (3 %)

1 (2 %)

0.75

 Coronary artery disease

13 (16 %)

6 (21 %)

7 (13 %)

0.59

 Sepsis-related cardiopathy

6 (6 %)

5 (17 %)

1 (2 %)

0.01

 Left ventricular ejection fraction <45 %

27 (33 %)

16 (55 %)

11 (21 %)

<0.01

Total ventilation duration (days)

13 ± 14

20 ± 15

8 ± 12

<0.01

Ventilation duration before the first SBT (days)

6 ± 7

6 ± 6

4 ± 5

0.06

Total duration of ICU stay (days)

17 ± 16

26 ± 16

12 ± 14

<0.01

ICU mortality

6 (7 %)

2 (7 %)

4 (8 %)

0.76

  1. Values are expressed as mean ± standard deviation or number and frequency (%)
  2. aPatients with at least one WiPO vs. patients without WiPO
  3. COPD chronic obstructive pulmonary disease, ICU intensive care unit, SBT spontaneous breathing trial, WiPO weaning-induced pulmonary oedema