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Table 1 Patient characteristics

From: Cerebrospinal fluid penetration of meropenem in neurocritical care patients with proven or suspected ventriculitis: a prospective observational study

Characteristic Data
Age, years, median (range) 52 (46–80)
Weight, kg, median (range) 76 (55–105)
Body mass index, kg/m2, median (range) 25.95 (20–33)
Sex, male/female 52.4 %/47.6 %
CrCL on day of inclusion, ml/minute, median (range) 120.1 (52.3–217.6)
CRP in serum on day of inclusion, mg/dl, median (range) 3.1 (0.4–36.7)
Interleukin-6 in serum on day of inclusion, pg/ml, median (range) 13.7 (2.4–274.0)
CSF drain in 24 h on day of inclusion, median (range) 183 (21–360)
Interleukin-6 in CSF on day of inclusion, pg/ml, median (range) 3398 (140–24,522)
Cells in CSF on day of inclusion, n/μl, median (range) 503 (4–2894)
Protein in CSF on day of inclusion, mg/L, median (range) 107 (13–303)
Glucose in CSF on day of inclusion, mg/dl, median (range) 72 (47–126)
Glucose CSF/serum ratio on day of inclusion, median (range) 0.55 (0.38–0.99)
SAPS II on day of inclusion 47 (13–62)
SAPS II on day of exclusion, median (range) 32 (13–61)
SOFA score on day of inclusion, median (range) 6 (1–12)
SOFA score on day of exclusion, median (range) 2.5 (0–8)
30-day mortality 0
  1. Abbreviations: CrCL Estimated creatinine clearance (calculated using the Cockcroft-Gault equation [16]), CRP C-reactive protein, CSF Cerebrospinal fluid, SOFA Sepsis-related Organ Failure Assessment, SAPS II Simplified Acute Physiology Score II