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Table 5 (abstract P17). Patient characteristics by infection status at the time of a first postoperative complication (n = 67)

From: Sepsis 2016 Paris

 

Post-hoc likelihood of infection

P-Value

No infection*

Undetermined

Confirmed infection

(N = 12)

(N = 19)

(N = 36)

Age, years

65.5 (61.0, 72.0)

67.0 (53.0, 73.0)

65.0 (59.0, 69.0)

0.90

Charlson Comorbidity Index

5.5 (0.0, 6.9)

6.4 (0.0, 6.4)

6.4 (5.1, 9.5)

0.15

SOFA score

5.0 (2.0, 6.0)

5.0 (3.0, 6.0)

6.0 (4.0, 8.0)

0.24

Complication onset, days after surgery

3.0 (2.0, 4.0)

5.0 (3.0, 11.0)

6.5 (3.0, 8.0)

0.09

ICU length of stay following onset complication, days

1.5 (1.0, 5.0)

2.0 (1.0, 4.0)

8.5 (4.5, 16.5)

<0.001

Hospital mortality

1 (8 %)

1 (5 %)

12 (33 %)

0.03

SIRS criteria

    

T > 38 °C or T < 36 °C

4 (33 %)

7 (37 %)

13 (36 %)

0.98

WBC <4 or >12 (109/ml)

4 (33 %)

10 (53 %)

23 (64 %)

0.18

Respiratory rate >20/min, PCO2 < 32 mmHg or mechanical ventilation

5 (42 %)

11 (58 %)

31 (86 %)

0.01

Heart rate >90/min

6 (50 %)

13 (68 %)

28 (78 %)

0.19

  1. The likelihood of infection was based on post hoc physician assessment using validated definitions [2]. Patients considered to have 'possible' infection were classified as undetermined; patients considered to have 'probable' or 'definite' infection were classified as confirmed. *These include 5 patients initially treated with antibiotics in whom infection was later ruled out, and 7 patients in whom infection was never clinically suspected
  2. Data show medians (Q1 – Q3) or n (%). SOFA = Sequential Organ Failure Assessment, SIRS = Systemic Inflammatory Response Syndrome, T = Temperature, WBC = White blood cell count