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Table 4 (abstract P16). Clinical characteristics of septic patients with features of MAS and ferritin concentrations >1200 ng/ml vs septic patients without features of MAS

From: Sepsis 2016 Paris

Biochemical Profile
  Septic Patients without MAS (n = 82) Septic Patients with MAS and Ferritin >1200 (n = 22) P value*
Ferritin, ng/ml, 0 hr mean (sd, median, range) [95 % CI] 444.65 (846.45, 213.90, 5.70-6536.00) [257.17, 632.12] 5584.60 (4561.20, 3535.00, 1345.30-17,502.00) [3561.90, 7607.20] <0.0001
IL-18, pg/ml, 0 hr mean (sd, median, range) [95 % CI] 558.13 (499.23, 408.62, 159.84-3107.64) [446.86, 669.41] 2625.30 (3513.40, 1252.40, 305.85-15,214.01) [1067.30, 4183.40] <0.0001
IFN-γ, pg/ml, 0 hr mean (sd, median, range) [95 % CI] 27.62 (71.38, 0.10, 0.10-590.33) [11.71, 43.53] 287.61 (997.26, 34.09, 0.10-4704.60) [−154.63, 729.85] 0.0287
IL-1β, pg/ml, 0 hr mean (sd, median, range) [95 % CI] 12.96 (29.25, 4.74, 0.08-183.43) [5.53, 20.38] 45.32 (94.76, 8.55, 0.08-395.15) [2.19, 88.46] 0.0074
Mortality
In-hospital mortality, % 9.8 63.6 <0.0001
90-day mortality, % 28.1 72.7 0.0003
  1. *The p values represent a comparison between the patients without features of MAS and the patients with features of MAS and ferritin concentrations >1200 ng/ml. We used Fisher’s Exact test for categorical measures and the Mann–Whitney U test for continuous and non-normally distributed measures