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Fig. 11 (abstract P11). | Critical Care

Fig. 11 (abstract P11).

From: Sepsis 2016 Paris

Fig. 11 (abstract P11).

Cathelicidin is upregulated after cecal-ligation and puncture induced sepsis in 129X1/SvJ (cnlp+/+) mice from which total RNA and protein were collected from distal ileums over a period of time for (a) real time PCR targeting clnp for mCRAMP. Genetic knockout of cnlp led to (b) reduced survival, (c) higher sepsis severity score and (d) increased bacterial DNAemia upon experimental sepsis. Error bars represents standard error of the mean. P < 0.05 denotes statistical significance, Mann–Whitney U-test

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