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Table 4 Risk factors in patients with VAE compared with patients with VAP in all included studies

From: Does ventilator-associated event surveillance detect ventilator-associated pneumonia in intensive care units? A systematic review and meta-analysis

 

Studies (n)

Patients with VAE (n)

Patients with VAP (n)

Estimate (OR/WMD)

95 % Confidence interval (%)

Heterogeneity

Publication biasc

Effect model

I 2 (%)

P

t value (Egger’s test)

P

VAC

 Age

1

37

121

0.00a

−5.89, 5.89

NA

NA

NA

NA

NA

 Sex (male/female)

3

551

255

0.85b

0.59, 1.21

20.60

0.28

−2.68

0.24

Fixed

 APACHE

1

387

83

5.00a

−1.67, 11.67

NA

NA

NA

NA

NA

 Ventilated duration (days)

3

569

299

−2.79a

−4.79, −0.80

0.00

0.81

−3.39

0.18

Fixed

 Death in hospital

5

857

393

1.49b

1.11, 2.01

53.10

0.07

−1.37

0.27

Fixed

 Length of stay (days)

  In hospital

4

1244

329

−4.27a

−7.00, −1.55

47.40

0.13

0.20

0.94

Fixed

  In ICU

2

802

81

−0.64a

−5.84, 4.55

74.50

0.05

NA

NA

Random

IVAC

 Age

1

31

121

0.00a

−6.63, 6.63

NA

NA

NA

NA

NA

 Sex (male/female)

3

406

268

1.05b

0.70, 1.59

0.00

0.46

0.29

0.82

Fixed

 APACHE

1

344

83

4.00a

−2.53, 10.53

NA

NA

NA

NA

NA

 Ventilated duration (days)

2

384

248

−2.89a

−5.58, −0.20

0.00

0.80

NA

NA

Fixed

 Death in hospital

4

446

423

1.76b

1.23, 2.52

0.00

0.77

0.50

0.67

Fixed

 Length of stay (days)

  In hospital

2

384

248

−5.86a

−9.46, −2.25

0.00

0.92

NA

NA

Fixed

  In ICU

0

0

0

NA

NA

NA

NA

NA

NA

NA

  1. aEstimate refers to weighted mean difference (WMD). bEstimate refers to odds ratio (OR). cEgger’s test was used to estimate publication bias in meta-analyses containing more than two individual studies. VAE ventilator-associated conditions (including ventilator-associated conditions (VAC), infection-related ventilated-associated conditions (IVAC), possible ventilator-associated pneumonia (VAP), and probable VAP), APACHE acute physiology and chronic health evaluation, NA not available