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Table 4 Multivariate logistic regression of association of AKI with initial serum chloride ([Cl-]0), maximal serum chloride ([Cl-]max), initial serum sodium (Na0) and maximal serum sodium(Namax)

From: Hyperchloremia and moderate increase in serum chloride are associated with acute kidney injury in severe sepsis and septic shock patients

 

OR

95 % confidence interval

p

Age

0.99

0.95

1.04

0.776

Sex (male)

0.40

0.09

1.77

0.228

Hypertension

0.68

0.13

3.70

0.656

APACHE II

1.55

1.19

2.03

0.001a

Serum lactate

1.60

0.84

3.04

0.155

Norepinephrine dosage

1.06

0.82

1.36

0.680

Ventilator requirement

3.95

0.57

27.44

0.165

[Cl-]0

0.87

0.70

1.10

0.240

[Cl-]max

1.28

1.02

1.62

0.037a

Δ[Cl-]

1.32

1.07

1.61

0.008a

Na0

1.01

0.76

1.35

0.825

Namax

1.03

0.81

1.31

0.825

  1. Multivariate logistic regression model was adjusted by incorporating all potentially confounding factors including age, gender, underlying diseases, initial serum lactate, APACHE II score and requirement of vasopressor and ventilator
  2. AKI acute kidney injury, OR odds ratio, APACHE Acute Physiology and Chronic Health Evaluation
  3. aIndicates statistical significance, p < 0.05